Topical NSAID (ophthalmic)
Nepafenac
Brand names: Nevanac
Adult dose
Dose: 1 drop TDS to operative eye, starting 1 day before surgery, continuing 14 days post-op (cataract)
Route: Topical (ophthalmic)
Frequency: TDS
Clinical pearls
- Prevention of post-cataract pain/inflammation and macular oedema
Contraindications
- Aspirin/NSAID hypersensitivity
- Ocular epithelial defect (caution)
- Late pregnancy
Side effects
- Stinging
- Corneal melt (rare with prolonged use)
- Delayed wound healing
Interactions
- Other topical NSAIDs
Reference: BNF; RCOphth; https://bnf.nice.org.uk/drugs/nepafenac/. Verify against your local formulary and the latest BNF before prescribing.
Related
Curated clinical cross-links plus same-class fallbacks.
Pathways
- Acute Red Eye / Vision Loss Screen · RCOphth 2020; NICE CKS
- Idiopathic Intracranial Hypertension · ABN; consensus 2018
- Acute Red Eye Assessment · RCOphth / AAO
- Acute Angle Closure Glaucoma · RCOphth / EGS Guidelines
- Retinal Detachment · RCOphth Guidelines / EURETINA
- Diabetic Retinopathy — Screening and Management · NICE NG28 2016 / NHS DES Programme