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Topical NSAID (ophthalmic)

Nepafenac

Brand names: Nevanac

Adult dose

Dose: 1 drop TDS to operative eye, starting 1 day before surgery, continuing 14 days post-op (cataract)
Route: Topical (ophthalmic)
Frequency: TDS

Clinical pearls

  • Prevention of post-cataract pain/inflammation and macular oedema

Contraindications

  • Aspirin/NSAID hypersensitivity
  • Ocular epithelial defect (caution)
  • Late pregnancy

Side effects

  • Stinging
  • Corneal melt (rare with prolonged use)
  • Delayed wound healing

Interactions

  • Other topical NSAIDs

Reference: BNF; RCOphth; https://bnf.nice.org.uk/drugs/nepafenac/. Verify against your local formulary and the latest BNF before prescribing.

Related

Curated clinical cross-links plus same-class fallbacks.