Ocular lubricant (HA + osmoprotectant)
Sodium hyaluronate with trehalose
Brand names: Thealoz Duo
Adult dose
Dose: 1 drop PRN (4-6× daily)
Route: Topical (ophthalmic)
Frequency: PRN
Clinical pearls
- Moderate-severe dry eye disease
- Trehalose protects corneal cells from osmotic stress
Contraindications
- Hypersensitivity
Side effects
- Transient blurred vision
- Mild irritation
Reference: BNF; https://bnf.nice.org.uk/drugs/sodium-hyaluronate-with-trehalose/. Verify against your local formulary and the latest BNF before prescribing.
Related
Curated clinical cross-links plus same-class fallbacks.
Calculators
- Corrected Sodium (Hyperglycaemia) · Electrolytes
- Hyponatraemia Cause Algorithm · Electrolyte Disorders
- MELD-Na Score · Liver Disease
- MELD-Na Score for Liver Cirrhosis · Hepatology
- Intraocular Pressure Stratification & Glaucoma Risk · Glaucoma
- Roper-Hall Classification of Chemical Ocular Burns · Ocular Trauma
Pathways
- Acute Red Eye / Vision Loss Screen · RCOphth 2020; NICE CKS
- Idiopathic Intracranial Hypertension · ABN; consensus 2018
- Acute Red Eye Assessment · RCOphth / AAO
- Acute Angle Closure Glaucoma · RCOphth / EGS Guidelines
- Retinal Detachment · RCOphth Guidelines / EURETINA
- Diabetic Retinopathy — Screening and Management · NICE NG28 2016 / NHS DES Programme