ClinCalc Pro
Menu
Calculators Drugs Pathways AI Dx Donate Get the App
Non-selective β-blocker (topical)

Timolol maleate

Brand names: Timoptol, Tiopex

Adult dose

Dose: 1 drop 0.25% or 0.5% BD (or gel-forming OD)
Route: Topical (ophthalmic)
Frequency: BD or OD

Clinical pearls

  • Open-angle glaucoma / OHT — 2nd-line after PG analogues
  • Punctal occlusion reduces systemic absorption

Contraindications

  • Asthma
  • Severe COPD
  • Severe bradycardia
  • 2nd/3rd degree AV block
  • Cardiogenic shock
  • Severe HF

Side effects

  • Bradycardia
  • Bronchospasm
  • Hypotension
  • Eye irritation
  • Systemic β-blocker effects

Interactions

  • Systemic β-blockers
  • Verapamil
  • Diltiazem

Monitoring

  • IOP
  • HR
  • Asthma symptoms

Reference: BNF; NICE NG81; https://bnf.nice.org.uk/drugs/timolol-maleate/. Verify against your local formulary and the latest BNF before prescribing.

Related

Curated clinical cross-links plus same-class fallbacks.

Calculators
Pathways