Prostaglandin + β-blocker
Travoprost with timolol
Brand names: DuoTrav
Adult dose
Dose: 1 drop in affected eye(s) OD
Route: Topical (ophthalmic)
Frequency: OD
Clinical pearls
- Open-angle glaucoma / OHT when monotherapy inadequate
- Punctal occlusion reduces systemic timolol absorption
Contraindications
- Asthma
- Severe COPD
- Severe bradycardia
- 2nd/3rd degree AV block
- Severe HF
Side effects
- Iris/lash pigmentation
- Conjunctival hyperaemia
- Bradycardia
- Bronchospasm
Interactions
- Systemic β-blockers
- CCBs
Monitoring
- IOP
- HR
- Asthma symptoms
Reference: BNF; NICE NG81; https://bnf.nice.org.uk/drugs/travoprost-with-timolol/. Verify against your local formulary and the latest BNF before prescribing.
Related
Curated clinical cross-links plus same-class fallbacks.
Calculators
Pathways
- Acute Red Eye / Vision Loss Screen · RCOphth 2020; NICE CKS
- Idiopathic Intracranial Hypertension · ABN; consensus 2018
- Acute Red Eye Assessment · RCOphth / AAO
- Acute Angle Closure Glaucoma · RCOphth / EGS Guidelines
- Retinal Detachment · RCOphth Guidelines / EURETINA
- Diabetic Retinopathy — Screening and Management · NICE NG28 2016 / NHS DES Programme