Beclometasone dipropionate

How it works

It is a glucocorticoid that, after local activation, suppresses airway inflammation by modulating gene expression to reduce inflammatory mediator production and cellular infiltration.

Prescribing in practice

• Different inhaler formulations are not interchangeable on a like-for-like basis, so prescribe and switch by brand to avoid dosing errors.
• It is a preventer requiring regular use and provides no immediate relief of acute bronchospasm.
• Oral candidiasis and dysphonia can occur, and high cumulative inhaled exposure carries systemic corticosteroid risks.

Monitoring

Monitor asthma control, inhaler technique, and in children growth, alongside vigilance for local oropharyngeal effects.

Counselling the patient

• Use every day as a preventer even when you feel well.
• Rinse your mouth after inhaling to reduce thrush and hoarseness.
• Carry your reliever inhaler for acute symptoms.

Evidence & guidelines

Inhaled corticosteroids are a cornerstone of asthma maintenance therapy in NICE and national asthma guidance.