Long-acting corticosteroid
Triamcinolone hexacetonide
Brand names: Lederspan
Adult dose
Dose: Intra-articular: 2–20mg per joint
Route: Intra-articular
Frequency: per indication
Clinical pearls
- Larger joints; longest-acting intra-articular steroid
- Limit to 3-4 injections per joint per year
Contraindications
- Joint infection
- Systemic infection
- Hypersensitivity
Side effects
- Joint damage with frequent injections
- HPA suppression
- Local atrophy
- Hyperglycaemia
Interactions
- Live vaccines
- Anticoagulants
Reference: BNF; BSR; https://bnf.nice.org.uk/drugs/triamcinolone-hexacetonide/. Verify against your local formulary and the latest BNF before prescribing.
Related
Curated clinical cross-links plus same-class fallbacks.
Calculators
Pathways
- Cutaneous Lupus Erythematosus · BAD; EULAR
- Osteoporosis / Fragility Fracture · NOGG 2021; NICE NG147; NG224
- Arteritic AION (Giant Cell Arteritis) · RCOphth; BSR
- Osteoarthritis Hip / Knee Management · NICE NG226 (2022)
- Lupus Nephritis · EULAR/ERA-EDTA 2019; KDIGO 2024
- Rheumatoid Arthritis Management · NICE CG79 2018 / EULAR 2022