OphthalmologyRheumatology
Arteritic AION (Giant Cell Arteritis)
Acute painless vision loss in elderly + GCA features; urgent high-dose steroid (do NOT wait for biopsy).
Source: RCOphth; BSR
Step 1 of ~2
info
Recognise
Arteritic anterior ischaemic optic neuropathy (A-AION): vasculitis of posterior ciliary artery → optic nerve infarction.
Features:
• Age ≥50, classically >65y.
• Sudden painless monocular vision loss (severe).
• Pale swollen optic disc on fundoscopy ('chalky white').
• ± altitudinal visual field defect.
• ± RAPD.
• GCA features: temporal headache, jaw claudication, scalp tenderness, polymyalgia, malaise, weight loss, fever.
Risk of contralateral involvement up to 75% within days-weeks if untreated.
Distinguish from non-arteritic AION (NA-AION):
• Younger, vasculopathic.
• Less severe vision loss.
• Disc swelling more variable.
• Crowded disc anatomy.
• Steroid less effective.
Related
Curated clinical cross-links plus same-class fallbacks.
Drugs
- Hydroxocobalamin (High-Dose — Cyanide Antidote) · Cyanide Antidote (Vitamin B12 Precursor at High Dose)
- Ascorbic Acid (Vitamin C — High-dose Burns) · Antioxidant / Capillary integrity support
- Colecalciferol 1000–2000 units/day · Vitamin D Supplement (Native Vitamin D3)
- Dopamine (ICU — Vasopressor/Inotrope) · Catecholamine (Dose-Dependent Vasopressor/Inotrope)
- Dopamine hydrochloride · Inotrope / vasopressor (dose-dependent)
- Glyceryl Trinitrate (Sublingual / IV) · Nitrate / Acute Angina
Pathways
- Acute Red Eye / Vision Loss Screen · RCOphth 2020; NICE CKS
- Idiopathic Intracranial Hypertension · ABN; consensus 2018
- Acute Red Eye Assessment · RCOphth / AAO
- Acute Angle Closure Glaucoma · RCOphth / EGS Guidelines
- Retinal Detachment · RCOphth Guidelines / EURETINA
- Diabetic Retinopathy — Screening and Management · NICE NG28 2016 / NHS DES Programme
Decision support only. Always apply local guidelines and clinical judgement.