Rheumatology Drugs

T-cell Co-stimulation Inhibitor (CTLA4-Ig)

CDK4/6 inhibitor

Androgen biosynthesis (CYP17) inhibitor

Bruton's tyrosine kinase (BTK) inhibitor

NSAID

Biologic DMARD (TNF-alpha inhibitor, monoclonal antibody)

Irreversible ErbB family TKI

VEGF-trap fusion protein

Recombinant α-galactosidase A (ERT)

Recombinant α-galactosidase A (ERT)

Recombinant interleukin-2

ALK tyrosine kinase inhibitor

Bisphosphonate — Oral (Weekly)

Enzyme Replacement Therapy (Lysosomal Storage Disorder)

Xanthine oxidase inhibitor / Urate-lowering therapy

PI3K Inhibitor (Specialist Oncology Drug)

EGFR/MET Bispecific Antibody (Specialist Oncology Drug)

Acridine Derivative Cytotoxic (Specialist Oncology Drug)

Platelet Reducing Agent (Specialist Drug)

IL-1 Receptor Antagonist

Type I Interferon Receptor Antagonist (Monoclonal Antibody)

Immunosuppressant (Polyclonal Anti-T-Cell Immunoglobulin)

Androgen Receptor Inhibitor (Specialist Oncology Drug)

Targeted Synthetic DMARD — Phosphodiesterase-4 (PDE4) Inhibitor

Differentiation Agent / Cytotoxic (Specialist Oncology Drug)

STAMP Inhibitor (BCR-ABL1 Myristoyl Pocket Inhibitor — Specialist Oncology Drug)

Enzyme Replacement Therapy (Hypophosphatasia — Tissue Non-specific Alkaline Phosphatase)

Enzyme Cytotoxic — Asparagine Depletion Agent (Specialist Oncology Drug)

Anti-PD-L1 Monoclonal Antibody — Immune Checkpoint Inhibitor (Specialist Oncology Drug)

DMARD (oral gold compound)

Complement C5a Receptor Antagonist (Oral Biologic)

Enzyme Replacement Therapy (Next-generation — Pompe Disease)

KIT/PDGFRA Kinase Inhibitor (Specialist Oncology Drug)

Anti-PD-L1 Monoclonal Antibody — Immune Checkpoint Inhibitor (Specialist Oncology Drug)

VEGFR Tyrosine Kinase Inhibitor (Specialist Oncology Drug)

DNA Methyltransferase Inhibitor / Hypomethylating Agent (Specialist Oncology Drug)

Conventional DMARD — Purine Antimetabolite

Live attenuated mycobacterial immunotherapy

JAK Inhibitor (JAK1/JAK2 Inhibitor)

Anti-BCMA antibody-drug conjugate (specialist)

Anti-BLyS Monoclonal Antibody (B-cell Inhibitor)

HIF-2α inhibitor (specialist)

Alkylating agent (specialist)

Uricosuric Agent — Potent URAT1 Inhibitor

Anti-VEGF monoclonal antibody (specialist)

Retinoid X receptor agonist (specialist)

Biologic DMARD — Dual IL-17A and IL-17F Inhibitor

MEK inhibitor (specialist)

Antitumour antibiotic (specialist)

CD3 × CD19 bispecific T-cell engager (specialist)

Proteasome inhibitor (specialist)

BCR-ABL TKI (specialist)

CD30 antibody-drug conjugate (specialist)

Dual TYK2/JAK1 Inhibitor (Investigational)

ALK inhibitor (specialist)

Alkylating agent (specialist)

Taxane (specialist)

Multi-kinase inhibitor (MET, VEGFR2, AXL, RET)

Anti-IL-1β Monoclonal Antibody

Oral fluoropyrimidine prodrug (specialist)

AKT inhibitor (specialist)

Topical analgesic (TRPV1 agonist)

Platinum-based alkylating agent (specialist)

Proteasome inhibitor (specialist)

Nitrosourea alkylating agent (specialist)

NSAID — Selective COX-2 Inhibitor

Anti-PD-1 monoclonal antibody (specialist)

ALK tyrosine-kinase inhibitor

TNF-α inhibitor (PEGylated Fab')

TNF-α Inhibitor (PEGylated Fab Fragment)

Anti-EGFR monoclonal antibody

Alkylating agent

Topical alkylating agent

Calcineurin inhibitor

Conventional DMARD — Calcineurin Inhibitor

Platinum chemotherapy

Purine nucleoside antimetabolite

MEK inhibitor

Anti-gout / Anti-inflammatory

L-asparaginase

ALK/ROS1 tyrosine-kinase inhibitor

Alkylating agent / immunosuppressant

Conventional DMARD — Alkylating Agent

Pyrimidine antimetabolite (specialist)

BRAF V600 inhibitor (specialist)

Alkylating agent (triazene, specialist)

Second-generation EGFR-TKI (specialist)

BCR-ABL TKI (specialist)

Anthracycline (specialist)

Liposomal anthracycline + pyrimidine analogue (specialist)

Hypomethylating agent (specialist)

Oral hypomethylating agent + cytidine deaminase inhibitor (specialist)

RANKL Inhibitor — Monoclonal Antibody

Selective TYK2 Inhibitor (Allosteric — Regulatory Domain Binding)

Corticosteroid — High Potency

NSAID (S-enantiomer of ketoprofen)

Cardioprotectant / anthracycline extravasation antidote

Non-selective NSAID

NSAID (rapid-onset salt)

NSAID (non-selective COX inhibitor)

NSAID + prostaglandin analogue (gastroprotective)

Synthetic non-steroidal oestrogen (legacy)

Anti-GD2 monoclonal antibody (specialist)

Taxane (microtubule inhibitor, specialist)

Anti-PD-1 monoclonal antibody (specialist)

Anthracycline (specialist)

Anti-PD-L1 monoclonal antibody (specialist)

Oral selective oestrogen receptor degrader (SERD, specialist)

Anti-SLAMF7 monoclonal antibody (specialist)

BRAF V600 inhibitor (specialist)

Nectin-4 antibody-drug conjugate (specialist)

Tropomyosin receptor kinase / ROS1 inhibitor (specialist)

CD3 × CD20 bispecific T-cell engager (specialist)

Anthracycline (specialist)

Pan-FGFR inhibitor (specialist)

Microtubule inhibitor (specialist)

EGFR tyrosine kinase inhibitor (specialist)

Conjugated oestrogen-nornitrogen mustard (specialist)

TNF-α Inhibitor (Fusion Protein)

NSAID (preferential COX-2)

Topoisomerase II inhibitor

Selective COX-2 Inhibitor

mTOR inhibitor

Xanthine Oxidase Inhibitor — Urate-Lowering Therapy

JAK2 inhibitor

Targeted Synthetic DMARD — Selective JAK1 Inhibitor

Purine analogue

Antimetabolite chemotherapy

VEGFR tyrosine-kinase inhibitor

FGFR1-4 tyrosine-kinase inhibitor

EGFR tyrosine-kinase inhibitor

Pyrimidine antimetabolite chemotherapy

Anti-CD33 antibody-drug conjugate

FLT3 tyrosine-kinase inhibitor

Histone deacetylase (HDAC) inhibitor

Hedgehog pathway inhibitor

CD20 × CD3 bispecific T-cell engager

TNF-α Inhibitor (Human Monoclonal Antibody)

Biologic DMARD — IL-23 Inhibitor (Anti-p19)

Antimalarial DMARD

Antimalarial / DMARD

Anti-BAFF Monoclonal Antibody (B-Cell Survival Factor Inhibitor)

BTK inhibitor

Anthracycline chemotherapy

PI3Kδ inhibitor

Alkylating agent

Prostacyclin Analogue — Vasodilator and Antiplatelet

BCR-ABL/c-KIT tyrosine-kinase inhibitor

Non-selective NSAID

NSAID — Non-selective COX Inhibitor

Anti-CD19 Monoclonal Antibody (B-Cell Depleting)

Anti-TNF-α monoclonal antibody

TNF-α Inhibitor (Chimeric Monoclonal Antibody)

Anti-CD22 antibody-drug conjugate

Anti-CTLA-4 monoclonal antibody (immune checkpoint inhibitor)

Topoisomerase I inhibitor

Anti-CD38 monoclonal antibody

IDH1 inhibitor

Proteasome inhibitor

Anti-IL-17A Monoclonal Antibody

HER2/EGFR tyrosine-kinase inhibitor

TRK tyrosine-kinase inhibitor

3rd-generation EGFR tyrosine-kinase inhibitor

DMARD (pyrimidine synthesis inhibitor)

Immunomodulatory drug (IMiD)

PI3Kδ inhibitor

Multi-kinase inhibitor (VEGFR/FGFR/RET/KIT)

Nitrosourea alkylating agent

Anti-CD19 antibody-drug conjugate

3rd-generation ALK/ROS1 tyrosine-kinase inhibitor

NSAID — Preferential COX-2 Inhibitor

Alkylating agent

Biologic — Anti-IL-5 Monoclonal Antibody

Folate antagonist / DMARD / antineoplastic

DMARD (Disease-Modifying Antirheumatic Drug) / Immunosuppressant

Corticosteroid

Intra-articular corticosteroid + LA

Multi-kinase inhibitor (FLT3, KIT)

Macrophage activator (MTP-PE)

Folate-receptor-α antibody-drug conjugate

Alkylating cytotoxic

Adrenocortical cytotoxic

Anthracenedione cytotoxic

Anti-CCR4 monoclonal antibody

JAK1/JAK2/ACVR1 inhibitor

CD20 × CD3 bispecific T-cell engager

Inosine monophosphate dehydrogenase inhibitor

Conventional DMARD — Inosine Monophosphate Dehydrogenase Inhibitor

Non-acidic NSAID prodrug

Non-selective NSAID

NSAID + PPI

Purine antimetabolite

Pan-HER tyrosine-kinase inhibitor

BCR-ABL tyrosine-kinase inhibitor (2nd gen)

Tyrosine Kinase Inhibitor — Anti-fibrotic

Anti-PD-1 immune checkpoint inhibitor

Anti-PD-1 + anti-LAG-3

Glycoengineered Type II Anti-CD20 Monoclonal Antibody

Type II anti-CD20 monoclonal antibody

PARP inhibitor

3rd-generation EGFR tyrosine-kinase inhibitor

Platinum chemotherapy

Taxane chemotherapy

CDK4/6 inhibitor

Anti-EGFR monoclonal antibody (fully human)

HDAC inhibitor

Multi-kinase inhibitor (VEGFR/PDGFR/c-KIT)

Pegylated L-asparaginase (specialist)

Recombinant Uricase — Urate-Lowering Biologic

Anti-PD-1 monoclonal antibody (immune checkpoint inhibitor)

Antifolate antineoplastic (specialist)

FGFR inhibitor (specialist)

Conventional DMARD — Chelating Agent

Adenosine deaminase inhibitor (purine analogue, specialist)

Anti-HER2 monoclonal antibody (dimerisation inhibitor)

Fixed-dose anti-HER2 combination

NSAID (oxicam)

Reversible non-covalent BTK inhibitor

Aza-anthracenedione cytotoxic

Immunomodulator (thalidomide analogue)

BCR-ABL tyrosine-kinase inhibitor

Selective RET kinase inhibitor

Corticosteroid (oral) — bridge/anti-inflammatory

Anticholinergic muscle relaxant

Uricosuric Agent — OAT Inhibitor

Hydrazine alkylating cytotoxic

FLT3 tyrosine-kinase inhibitor

Thymidylate synthase inhibitor

Anti-VEGFR2 monoclonal antibody

Multi-kinase inhibitor

CDK4/6 inhibitor

IL-1α/β and IL-18 Fusion Protein Trap

Switch-control KIT/PDGFRA tyrosine-kinase inhibitor

Biologic DMARD — IL-23 Inhibitor (Anti-p19)

Anti-CD20 monoclonal antibody

Biologic DMARD — Anti-CD20

Anti-Sclerostin Monoclonal Antibody (Dual Anabolic/Anti-Resorptive)

PARP inhibitor

Biologic DMARD — IL-6 Receptor Antagonist

Anti-IL-17A Monoclonal Antibody

Selective RET kinase inhibitor

Anti-PD-1 monoclonal antibody

Phosphodiesterase-5 (PDE5) Inhibitor

Anti-IL-6 monoclonal antibody

mTOR inhibitor (immunosuppressant)

Conventional DMARD — Gold Salt (Historical DMARD)

KRAS G12C inhibitor

Nitrosourea cytotoxic

DMARD / Anti-inflammatory

NSAID (prodrug)

PARP inhibitor

Oncolytic HSV-1 (genetically modified)

Bispecific GPRC5D × CD3 antibody

Selective oestrogen receptor modulator (SERM)

Bispecific DLL3 × CD3 T-cell engager

Bispecific gp100 × CD3 (ImmTAC)

Oral fluoropyrimidine combination (S-1)

TACI-Fc Fusion Protein (Dual APRIL and BLyS Inhibitor)

Photosensitiser

Alkylating cytotoxic

mTOR inhibitor

NSAID (oxicam)

Selective MET kinase inhibitor

Immunomodulatory Drug (IMiD)

Alkylating cytotoxic

NSAID

Thiopurine antimetabolite

VEGFR tyrosine-kinase inhibitor

Biologic DMARD (IL-6 receptor antagonist)

JAK Inhibitor (JAK1/JAK3 Inhibitor)

Topoisomerase I inhibitor

Selective oestrogen receptor modulator (SERM)

Marine-derived alkylating cytotoxic

MEK inhibitor

Anti-HER2 monoclonal antibody

Anti-HER2 antibody-drug conjugate

Anti-HER2 antibody-drug conjugate

Anti-CTLA-4 monoclonal antibody

Alkylating cytotoxic

Retinoid (ATRA)

Intermediate-acting corticosteroid

Corticosteroid — Intra-articular / Intramuscular

Long-acting corticosteroid

Oral fluoropyrimidine + thymidine phosphorylase inhibitor

HER2 selective tyrosine-kinase inhibitor

JAK Inhibitor (Selective JAK1 Inhibitor)

Multi-kinase inhibitor (RET, EGFR, VEGFR)

BRAF V600 inhibitor

Vinca alkaloid cytotoxic

Vinca alkaloid cytotoxic

Vinca alkaloid cytotoxic

Vinca alkaloid cytotoxic

Hedgehog pathway (SMO) inhibitor

Calcineurin Inhibitor (CNI) — Cyclosporin Analogue

Dual IDH1/2 inhibitor

CLDN18.2-targeting monoclonal antibody (specialist)

Bisphosphonate — Intravenous (Annual)