Rheumatology Drugs

297 drugs

Quick-reference dosing for 297 rheumatology medicines, aligned to current UK formularies. Each entry lists adult, paediatric and (where relevant) neonatal doses, renal and hepatic adjustments, contraindications, key interactions, monitoring and clinical pearls — with the source reference. Always confirm doses against current prescribing references before prescribing.

Abatacept

T-cell Co-stimulation Inhibitor (CTLA4-Ig)
Abemaciclib [Specialist drug]

CDK4/6 inhibitor
Abiraterone acetate

Androgen biosynthesis (CYP17) inhibitor
Acalabrutinib [Specialist drug]

Bruton's tyrosine kinase (BTK) inhibitor
Aceclofenac

NSAID
Adalimumab

Biologic DMARD (TNF-alpha inhibitor, monoclonal antibody)
Afatinib [Specialist drug]

Irreversible ErbB family TKI
Aflibercept [Specialist drug]

VEGF-trap fusion protein
Agalsidase alfa

Recombinant α-galactosidase A (ERT)
Agalsidase beta

Recombinant α-galactosidase A (ERT)
Aldesleukin [Specialist drug]

Recombinant interleukin-2
Alectinib [Specialist drug]

ALK tyrosine kinase inhibitor
Alendronic Acid (Rheumatology — Osteoporosis)

Bisphosphonate — Oral (Weekly)
Alglucosidase Alfa

Enzyme Replacement Therapy (Lysosomal Storage Disorder)
Allopurinol

Xanthine oxidase inhibitor / Urate-lowering therapy
Alpelisib

PI3K Inhibitor (Specialist Oncology Drug)
Amivantamab

EGFR/MET Bispecific Antibody (Specialist Oncology Drug)
Amsacrine

Acridine Derivative Cytotoxic (Specialist Oncology Drug)
Anagrelide

Platelet Reducing Agent (Specialist Drug)
Anakinra

IL-1 Receptor Antagonist
Anifrolumab (Type I IFN Receptor Inhibitor — SLE)

Type I Interferon Receptor Antagonist (Monoclonal Antibody)
Antithymocyte Immunoglobulin (Rabbit)

Immunosuppressant (Polyclonal Anti-T-Cell Immunoglobulin)
Apalutamide

Androgen Receptor Inhibitor (Specialist Oncology Drug)
Apremilast

Targeted Synthetic DMARD — Phosphodiesterase-4 (PDE4) Inhibitor
Arsenic Trioxide

Differentiation Agent / Cytotoxic (Specialist Oncology Drug)
Asciminib

STAMP Inhibitor (BCR-ABL1 Myristoyl Pocket Inhibitor — Specialist Oncology Drug)
Asfotase Alfa

Enzyme Replacement Therapy (Hypophosphatasia — Tissue Non-specific Alkaline Phosphatase)
Asparaginase

Enzyme Cytotoxic — Asparagine Depletion Agent (Specialist Oncology Drug)
Atezolizumab

Anti-PD-L1 Monoclonal Antibody — Immune Checkpoint Inhibitor (Specialist Oncology Drug)
Auranofin

DMARD (oral gold compound)
Avacopan (C5a Receptor Inhibitor — ANCA Vasculitis)

Complement C5a Receptor Antagonist (Oral Biologic)
Avalglucosidase Alfa

Enzyme Replacement Therapy (Next-generation — Pompe Disease)
Avapritinib

KIT/PDGFRA Kinase Inhibitor (Specialist Oncology Drug)
Avelumab

Anti-PD-L1 Monoclonal Antibody — Immune Checkpoint Inhibitor (Specialist Oncology Drug)
Axitinib

VEGFR Tyrosine Kinase Inhibitor (Specialist Oncology Drug)
Azacitidine

DNA Methyltransferase Inhibitor / Hypomethylating Agent (Specialist Oncology Drug)
Azathioprine (Rheumatology)

Conventional DMARD — Purine Antimetabolite
Bacillus Calmette-Guérin (intravesical)

Live attenuated mycobacterial immunotherapy
Baricitinib

JAK Inhibitor (JAK1/JAK2 Inhibitor)
Belantamab mafodotin

Anti-BCMA antibody-drug conjugate (specialist)
Belimumab

Anti-BLyS Monoclonal Antibody (B-cell Inhibitor)
Belzutifan

HIF-2α inhibitor (specialist)
Bendamustine hydrochloride

Alkylating agent (specialist)
Benzbromarone

Uricosuric Agent — Potent URAT1 Inhibitor
Bevacizumab

Anti-VEGF monoclonal antibody (specialist)
Bexarotene

Retinoid X receptor agonist (specialist)
Bimekizumab

Biologic DMARD — Dual IL-17A and IL-17F Inhibitor
Binimetinib

MEK inhibitor (specialist)
Bleomycin

Antitumour antibiotic (specialist)
Blinatumomab

CD3 × CD19 bispecific T-cell engager (specialist)
Bortezomib

Proteasome inhibitor (specialist)
Bosutinib

BCR-ABL TKI (specialist)
Brentuximab vedotin

CD30 antibody-drug conjugate (specialist)
Brepocitinib (TYK2/JAK1 Inhibitor — Dermatomyositis)

Dual TYK2/JAK1 Inhibitor (Investigational)
Brigatinib

ALK inhibitor (specialist)
Busulfan

Alkylating agent (specialist)
Cabazitaxel

Taxane (specialist)
Cabozantinib

Multi-kinase inhibitor (MET, VEGFR2, AXL, RET)
Canakinumab

Anti-IL-1β Monoclonal Antibody
Capecitabine

Oral fluoropyrimidine prodrug (specialist)
Capivasertib

AKT inhibitor (specialist)
Capsaicin

Topical analgesic (TRPV1 agonist)
Carboplatin

Platinum-based alkylating agent (specialist)
Carfilzomib

Proteasome inhibitor (specialist)
Carmustine

Nitrosourea alkylating agent (specialist)
Celecoxib (Rheumatology)

NSAID — Selective COX-2 Inhibitor
Cemiplimab

Anti-PD-1 monoclonal antibody (specialist)
Ceritinib (Specialist drug)

ALK tyrosine-kinase inhibitor
Certolizumab pegol

TNF-α inhibitor (PEGylated Fab')
Certolizumab Pegol

TNF-α Inhibitor (PEGylated Fab Fragment)
Cetuximab (Specialist drug)

Anti-EGFR monoclonal antibody
Chlorambucil (Specialist drug)

Alkylating agent
Chlormethine (Specialist drug)

Topical alkylating agent
Ciclosporin

Calcineurin inhibitor
Ciclosporin (Rheumatology)

Conventional DMARD — Calcineurin Inhibitor
Cisplatin (Specialist drug)

Platinum chemotherapy
Clofarabine (Specialist drug)

Purine nucleoside antimetabolite
Cobimetinib (Specialist drug)

MEK inhibitor
Colchicine

Anti-gout / Anti-inflammatory
Crisantaspase (Specialist drug)

L-asparaginase
Crizotinib (Specialist drug)

ALK/ROS1 tyrosine-kinase inhibitor
Cyclophosphamide

Alkylating agent / immunosuppressant
Cyclophosphamide (Rheumatology)

Conventional DMARD — Alkylating Agent
Cytarabine

Pyrimidine antimetabolite (specialist)
Dabrafenib

BRAF V600 inhibitor (specialist)
Dacarbazine

Alkylating agent (triazene, specialist)
Dacomitinib

Second-generation EGFR-TKI (specialist)
Dasatinib

BCR-ABL TKI (specialist)
Daunorubicin

Anthracycline (specialist)
Daunorubicin with cytarabine

Liposomal anthracycline + pyrimidine analogue (specialist)
Decitabine

Hypomethylating agent (specialist)
Decitabine with cedazuridine

Oral hypomethylating agent + cytidine deaminase inhibitor (specialist)
Denosumab (Rheumatology — Osteoporosis)

RANKL Inhibitor — Monoclonal Antibody
Deucravacitinib (TYK2 Inhibitor — Psoriatic Arthritis/Psoriasis)

Selective TYK2 Inhibitor (Allosteric — Regulatory Domain Binding)
Dexamethasone (Rheumatology)

Corticosteroid — High Potency
Dexketoprofen

NSAID (S-enantiomer of ketoprofen)
Dexrazoxane

Cardioprotectant / anthracycline extravasation antidote
Diclofenac (Rheumatology)

Non-selective NSAID
Diclofenac potassium

NSAID (rapid-onset salt)
Diclofenac sodium

NSAID (non-selective COX inhibitor)
Diclofenac sodium with misoprostol

NSAID + prostaglandin analogue (gastroprotective)
Diethylstilbestrol

Synthetic non-steroidal oestrogen (legacy)
Dinutuximab beta

Anti-GD2 monoclonal antibody (specialist)
Docetaxel

Taxane (microtubule inhibitor, specialist)
Dostarlimab

Anti-PD-1 monoclonal antibody (specialist)
Doxorubicin hydrochloride

Anthracycline (specialist)
Durvalumab

Anti-PD-L1 monoclonal antibody (specialist)
Elacestrant

Oral selective oestrogen receptor degrader (SERD, specialist)
Elotuzumab

Anti-SLAMF7 monoclonal antibody (specialist)
Encorafenib

BRAF V600 inhibitor (specialist)
Enfortumab vedotin

Nectin-4 antibody-drug conjugate (specialist)
Entrectinib

Tropomyosin receptor kinase / ROS1 inhibitor (specialist)
Epcoritamab

CD3 × CD20 bispecific T-cell engager (specialist)
Epirubicin hydrochloride

Anthracycline (specialist)
Erdafitinib

Pan-FGFR inhibitor (specialist)
Eribulin

Microtubule inhibitor (specialist)
Erlotinib

EGFR tyrosine kinase inhibitor (specialist)
Estramustine phosphate

Conjugated oestrogen-nornitrogen mustard (specialist)
Etanercept

TNF-α Inhibitor (Fusion Protein)
Etodolac

NSAID (preferential COX-2)
Etoposide (Specialist drug)

Topoisomerase II inhibitor
Etoricoxib

Selective COX-2 Inhibitor
Everolimus

mTOR inhibitor
Febuxostat (Rheumatology — Gout)

Xanthine Oxidase Inhibitor — Urate-Lowering Therapy
Fedratinib (Specialist drug)

JAK2 inhibitor
Filgotinib

Targeted Synthetic DMARD — Selective JAK1 Inhibitor
Fludarabine phosphate (Specialist drug)

Purine analogue
Fluorouracil (5-FU)

Antimetabolite chemotherapy
Fruquintinib (Specialist drug)

VEGFR tyrosine-kinase inhibitor
Futibatinib (Specialist drug)

FGFR1-4 tyrosine-kinase inhibitor
Gefitinib (Specialist drug)

EGFR tyrosine-kinase inhibitor
Gemcitabine (Specialist drug)

Pyrimidine antimetabolite chemotherapy
Gemtuzumab ozogamicin (Specialist drug)

Anti-CD33 antibody-drug conjugate
Gilteritinib (Specialist drug)

FLT3 tyrosine-kinase inhibitor
Givinostat

Histone deacetylase (HDAC) inhibitor
Glasdegib (Specialist drug)

Hedgehog pathway inhibitor
Glofitamab (Specialist drug)

CD20 × CD3 bispecific T-cell engager
Golimumab

TNF-α Inhibitor (Human Monoclonal Antibody)
Guselkumab

Biologic DMARD — IL-23 Inhibitor (Anti-p19)
Hydroxychloroquine

Antimalarial DMARD
Hydroxychloroquine sulfate

Antimalarial / DMARD
Ianalumab (Anti-BAFF — Primary Sjögren's Syndrome)

Anti-BAFF Monoclonal Antibody (B-Cell Survival Factor Inhibitor)
Ibrutinib (Specialist drug)

BTK inhibitor
Idarubicin (Specialist drug)

Anthracycline chemotherapy
Idelalisib (Specialist drug)

PI3Kδ inhibitor
Ifosfamide (Specialist drug)

Alkylating agent
Iloprost (Raynaud's / Systemic Sclerosis)

Prostacyclin Analogue — Vasodilator and Antiplatelet
Imatinib (Specialist drug)

BCR-ABL/c-KIT tyrosine-kinase inhibitor
Indometacin

Non-selective NSAID
Indomethacin (Indometacin)

NSAID — Non-selective COX Inhibitor
Inebilizumab (Anti-CD19 — IgG4-Related Disease)

Anti-CD19 Monoclonal Antibody (B-Cell Depleting)
Infliximab

Anti-TNF-α monoclonal antibody
Infliximab (Rheumatology)

TNF-α Inhibitor (Chimeric Monoclonal Antibody)
Inotuzumab ozogamicin (Specialist drug)

Anti-CD22 antibody-drug conjugate
Ipilimumab (Specialist drug)

Anti-CTLA-4 monoclonal antibody (immune checkpoint inhibitor)
Irinotecan (Specialist drug)

Topoisomerase I inhibitor
Isatuximab (Specialist drug)

Anti-CD38 monoclonal antibody
Ivosidenib (Specialist drug)

IDH1 inhibitor
Ixazomib (Specialist drug)

Proteasome inhibitor
Ixekizumab

Anti-IL-17A Monoclonal Antibody
Lapatinib (Specialist drug)

HER2/EGFR tyrosine-kinase inhibitor
Larotrectinib (Specialist drug)

TRK tyrosine-kinase inhibitor
Lazertinib (Specialist drug)

3rd-generation EGFR tyrosine-kinase inhibitor
Leflunomide

DMARD (pyrimidine synthesis inhibitor)
Lenalidomide (Specialist drug)

Immunomodulatory drug (IMiD)
Leniolisib

PI3Kδ inhibitor
Lenvatinib (Specialist drug)

Multi-kinase inhibitor (VEGFR/FGFR/RET/KIT)
Lomustine (Specialist drug)

Nitrosourea alkylating agent
Loncastuximab tesirine (Specialist drug)

Anti-CD19 antibody-drug conjugate
Lorlatinib (Specialist drug)

3rd-generation ALK/ROS1 tyrosine-kinase inhibitor
Meloxicam

NSAID — Preferential COX-2 Inhibitor
Melphalan (Specialist drug)

Alkylating agent
Mepolizumab (Eosinophilic GPA)

Biologic — Anti-IL-5 Monoclonal Antibody
Methotrexate

Folate antagonist / DMARD / antineoplastic
Methotrexate (Low-dose)

DMARD (Disease-Modifying Antirheumatic Drug) / Immunosuppressant
Methylprednisolone (IV Pulse)

Corticosteroid
Methylprednisolone with lidocaine

Intra-articular corticosteroid + LA
Midostaurin (Specialist drug)

Multi-kinase inhibitor (FLT3, KIT)
Mifamurtide (Specialist drug)

Macrophage activator (MTP-PE)
Mirvetuximab soravtansine (Specialist drug)

Folate-receptor-α antibody-drug conjugate
Mitomycin (Specialist drug)

Alkylating cytotoxic
Mitotane (Specialist drug)

Adrenocortical cytotoxic
Mitoxantrone (Specialist drug)

Anthracenedione cytotoxic
Mogamulizumab (Specialist drug)

Anti-CCR4 monoclonal antibody
Momelotinib (Specialist drug)

JAK1/JAK2/ACVR1 inhibitor
Mosunetuzumab (Specialist drug)

CD20 × CD3 bispecific T-cell engager
Mycophenolate mofetil

Inosine monophosphate dehydrogenase inhibitor
Mycophenolate Mofetil (Rheumatology)

Conventional DMARD — Inosine Monophosphate Dehydrogenase Inhibitor
Nabumetone

Non-acidic NSAID prodrug
Naproxen

Non-selective NSAID
Naproxen with esomeprazole

NSAID + PPI
Nelarabine (Specialist drug)

Purine antimetabolite
Neratinib (Specialist drug)

Pan-HER tyrosine-kinase inhibitor
Nilotinib (Specialist drug)

BCR-ABL tyrosine-kinase inhibitor (2nd gen)
Nintedanib (SSc-ILD)

Tyrosine Kinase Inhibitor — Anti-fibrotic
Nivolumab (Specialist drug)

Anti-PD-1 immune checkpoint inhibitor
Nivolumab with relatlimab (Specialist drug)

Anti-PD-1 + anti-LAG-3
Obinutuzumab (Anti-CD20 — Lupus Nephritis)

Glycoengineered Type II Anti-CD20 Monoclonal Antibody
Obinutuzumab (Specialist drug)

Type II anti-CD20 monoclonal antibody
Olaparib (Specialist drug)

PARP inhibitor
Osimertinib (Specialist drug)

3rd-generation EGFR tyrosine-kinase inhibitor
Oxaliplatin (Specialist drug)

Platinum chemotherapy
Paclitaxel (Specialist drug)

Taxane chemotherapy
Palbociclib (Specialist drug)

CDK4/6 inhibitor
Panitumumab (Specialist drug)

Anti-EGFR monoclonal antibody (fully human)
Panobinostat (Specialist drug)

HDAC inhibitor
Pazopanib (Specialist drug)

Multi-kinase inhibitor (VEGFR/PDGFR/c-KIT)
Pegaspargase

Pegylated L-asparaginase (specialist)
Pegloticase (Recombinant PEGylated Uricase — Refractory Gout)

Recombinant Uricase — Urate-Lowering Biologic
Pembrolizumab

Anti-PD-1 monoclonal antibody (immune checkpoint inhibitor)
Pemetrexed

Antifolate antineoplastic (specialist)
Pemigatinib

FGFR inhibitor (specialist)
Penicillamine

Conventional DMARD — Chelating Agent
Pentostatin

Adenosine deaminase inhibitor (purine analogue, specialist)
Pertuzumab (Specialist drug)

Anti-HER2 monoclonal antibody (dimerisation inhibitor)
Pertuzumab with trastuzumab (Specialist drug)

Fixed-dose anti-HER2 combination
Piroxicam

NSAID (oxicam)
Pirtobrutinib (Specialist drug)

Reversible non-covalent BTK inhibitor
Pixantrone (Specialist drug)

Aza-anthracenedione cytotoxic
Pomalidomide (Specialist drug)

Immunomodulator (thalidomide analogue)
Ponatinib (Specialist drug)

BCR-ABL tyrosine-kinase inhibitor
Pralsetinib (Specialist drug)

Selective RET kinase inhibitor
Prednisolone (Rheumatology)

Corticosteroid (oral) — bridge/anti-inflammatory
Pridinol

Anticholinergic muscle relaxant
Probenecid

Uricosuric Agent — OAT Inhibitor
Procarbazine (Specialist drug)

Hydrazine alkylating cytotoxic
Quizartinib (Specialist drug)

FLT3 tyrosine-kinase inhibitor
Raltitrexed (Specialist drug)

Thymidylate synthase inhibitor
Ramucirumab (Specialist drug)

Anti-VEGFR2 monoclonal antibody
Regorafenib (Specialist drug)

Multi-kinase inhibitor
Ribociclib (Specialist drug)

CDK4/6 inhibitor
Rilonacept (IL-1 Trap — Recurrent Pericarditis)

IL-1α/β and IL-18 Fusion Protein Trap
Ripretinib (Specialist drug)

Switch-control KIT/PDGFRA tyrosine-kinase inhibitor
Risankizumab (Rheumatology)

Biologic DMARD — IL-23 Inhibitor (Anti-p19)
Rituximab

Anti-CD20 monoclonal antibody
Rituximab (Rheumatology)

Biologic DMARD — Anti-CD20
Romosozumab (Anti-Sclerostin — Severe Osteoporosis)

Anti-Sclerostin Monoclonal Antibody (Dual Anabolic/Anti-Resorptive)
Rucaparib (Specialist drug)

PARP inhibitor
Sarilumab

Biologic DMARD — IL-6 Receptor Antagonist
Secukinumab

Anti-IL-17A Monoclonal Antibody
Selpercatinib (Specialist drug)

Selective RET kinase inhibitor
Serplulimab (Specialist drug)

Anti-PD-1 monoclonal antibody
Sildenafil (CTD-Associated PAH / Raynaud's)

Phosphodiesterase-5 (PDE5) Inhibitor
Siltuximab

Anti-IL-6 monoclonal antibody
Sirolimus

mTOR inhibitor (immunosuppressant)
Sodium Aurothiomalate (Gold)

Conventional DMARD — Gold Salt (Historical DMARD)
Sotorasib (Specialist drug)

KRAS G12C inhibitor
Streptozocin (Specialist drug)

Nitrosourea cytotoxic
Sulfasalazine

DMARD / Anti-inflammatory
Sulindac

NSAID (prodrug)
Talazoparib (Specialist drug)

PARP inhibitor
Talimogene laherparepvec (Specialist drug)

Oncolytic HSV-1 (genetically modified)
Talquetamab (Specialist drug)

Bispecific GPRC5D × CD3 antibody
Tamoxifen

Selective oestrogen receptor modulator (SERM)
Tarlatamab (Specialist drug)

Bispecific DLL3 × CD3 T-cell engager
Tebentafusp (Specialist drug)

Bispecific gp100 × CD3 (ImmTAC)
Tegafur with gimeracil and oteracil (Specialist drug)

Oral fluoropyrimidine combination (S-1)
Telitacicept (APRIL/BLyS Dual Inhibitor — SLE/IgA Nephropathy)

TACI-Fc Fusion Protein (Dual APRIL and BLyS Inhibitor)
Temoporfin (Specialist drug)

Photosensitiser
Temozolomide (Specialist drug)

Alkylating cytotoxic
Temsirolimus (Specialist drug)

mTOR inhibitor
Tenoxicam

NSAID (oxicam)
Tepotinib (Specialist drug)

Selective MET kinase inhibitor
Thalidomide (Rheumatology / Dermatology)

Immunomodulatory Drug (IMiD)
Thiotepa (Specialist drug)

Alkylating cytotoxic
Tiaprofenic acid

NSAID
Tioguanine (Specialist drug)

Thiopurine antimetabolite
Tivozanib (Specialist drug)

VEGFR tyrosine-kinase inhibitor
Tocilizumab

Biologic DMARD (IL-6 receptor antagonist)
Tofacitinib

JAK Inhibitor (JAK1/JAK3 Inhibitor)
Topotecan (Specialist drug)

Topoisomerase I inhibitor
Toremifene

Selective oestrogen receptor modulator (SERM)
Trabectedin (Specialist drug)

Marine-derived alkylating cytotoxic
Trametinib (Specialist drug)

MEK inhibitor
Trastuzumab (Specialist drug)

Anti-HER2 monoclonal antibody
Trastuzumab deruxtecan (Specialist drug)

Anti-HER2 antibody-drug conjugate
Trastuzumab emtansine (Specialist drug)

Anti-HER2 antibody-drug conjugate
Tremelimumab (Specialist drug)

Anti-CTLA-4 monoclonal antibody
Treosulfan (Specialist drug)

Alkylating cytotoxic
Tretinoin (Specialist drug)

Retinoid (ATRA)
Triamcinolone acetonide

Intermediate-acting corticosteroid
Triamcinolone Acetonide (Intra-articular)

Corticosteroid — Intra-articular / Intramuscular
Triamcinolone hexacetonide

Long-acting corticosteroid
Trifluridine with tipiracil (Specialist drug)

Oral fluoropyrimidine + thymidine phosphorylase inhibitor
Tucatinib (Specialist drug)

HER2 selective tyrosine-kinase inhibitor
Upadacitinib

JAK Inhibitor (Selective JAK1 Inhibitor)
Vandetanib (Specialist drug)

Multi-kinase inhibitor (RET, EGFR, VEGFR)
Vemurafenib (Specialist drug)

BRAF V600 inhibitor
Vinblastine sulfate (Specialist drug)

Vinca alkaloid cytotoxic
Vincristine sulfate (Specialist drug)

Vinca alkaloid cytotoxic
Vindesine sulfate (Specialist drug)

Vinca alkaloid cytotoxic
Vinorelbine (Specialist drug)

Vinca alkaloid cytotoxic
Vismodegib (Specialist drug)

Hedgehog pathway (SMO) inhibitor
Voclosporin (Calcineurin Inhibitor — Lupus Nephritis)

Calcineurin Inhibitor (CNI) — Cyclosporin Analogue
Vorasidenib (Specialist drug)

Dual IDH1/2 inhibitor
Zolbetuximab

CLDN18.2-targeting monoclonal antibody (specialist)
Zoledronic Acid (Rheumatology — Osteoporosis)

Bisphosphonate — Intravenous (Annual)