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Sclerosant

Sodium tetradecyl sulfate

Brand names: Fibrovein, Sotradecol

Adult dose

Dose: 0.1–1mL of 0.2–3% solution per injection — depends on vein size; specialist
Route: Intravenous (sclerotherapy)
Frequency: per session

Clinical pearls

  • Varicose vein sclerotherapy; foam preparation for larger veins
  • Specialist vascular; doppler/duplex pre-treatment

Contraindications

  • Acute DVT
  • Local/systemic infection
  • Severe peripheral vascular disease
  • Hypersensitivity
  • Pregnancy

Side effects

  • Pain at site
  • Skin necrosis if extravasation
  • Hyperpigmentation
  • DVT
  • Anaphylaxis
  • Stroke (if PFO with foam sclerotherapy)

Reference: BNF; NICE CG168/IPG440; SmPC; https://bnf.nice.org.uk/drugs/sodium-tetradecyl-sulfate/. Verify against your local formulary and the latest BNF before prescribing.

Related

Curated clinical cross-links plus same-class fallbacks.