GI & Hepatology Pathways

19 pathways

Work through 19 interactive gi & hepatology decision pathways — branching, guideline-grounded workflows that take you from presentation to assessment, risk stratification and management. Each pathway cites its source (NICE, ESC, AHA and specialty guidance), embeds the relevant calculators, and makes escalation and safety-netting explicit. For decision support only — apply clinical judgement and local protocols.

Acute Liver Failure

Assessment and management of acute liver failure including Kings College criteria for transplant

EASL 2017 / BSG
Decompensated Cirrhosis

Management of acute decompensation in cirrhosis — ascites, encephalopathy, SBP, variceal bleeding

BSG 2015 / EASL 2018
IBD Acute Flare Assessment

Assessment and management of acute flares in Crohn's disease and ulcerative colitis

ECCO / BSG 2019
Hepatitis B Management

Assessment of hepatitis B infection — acute vs chronic, treatment indications, monitoring

EASL 2017 / NICE NG33
Dysphagia Assessment Pathway

Systematic assessment of dysphagia — oropharyngeal vs oesophageal, urgent red flags

BSG 2010 / NICE NG12
Lower Gastrointestinal Bleed

Lower Gastrointestinal Bleed clinical pathway.

NICE; BSG; ACPGBI — Commissioning Guide
Acute Pancreatitis

Acute Pancreatitis clinical pathway.

NICE; IAP/APA; ACPGBI — CG104
Variceal Upper GI Bleed

BSG / Baveno VII — resuscitation, vasoactive drugs, antibiotics, urgent endoscopy with banding/glue, TIPS, secondary prevention.

BSG 2015; Baveno VII (2022)
Spontaneous Bacterial Peritonitis (SBP)

Diagnostic paracentesis, antibiotics, albumin infusion, secondary prophylaxis with norfloxacin / cipro.

BSG / EASL 2018
Hepatorenal Syndrome

EASL/ICA — diagnosis of exclusion in cirrhosis, AKI workup, terlipressin + albumin, transplant referral.

EASL 2018; ICA 2015
Hepatic Encephalopathy

Identify precipitants, lactulose to titrate to 2–3 soft stools/day, rifaximin for prevention, transplant referral.

EASL 2014; West Haven criteria
Clostridioides difficile Colitis

NICE NG199 / IDSA — recognition, severity stratification, antibiotic choice (vancomycin / fidaxomicin), recurrence prevention.

NICE NG199 (2021); IDSA/SHEA 2021
Acute Severe Ulcerative Colitis

Truelove and Witts criteria, IV steroids, infliximab/ciclosporin rescue, surgical referral on day 3 if no response.

BSG 2019; ECCO 2022
Crohn's Disease Flare

ECCO/BSG — assess severity (HBI), exclude infection, induction therapy (steroid / EEN / biologic), maintenance.

BSG 2019; ECCO 2020
Coeliac Disease Workup

NICE NG20 — serology (anti-tTG IgA + total IgA), biopsy confirmation, gluten-free diet, surveillance for complications.

NICE NG20; BSG 2014
Autoimmune Hepatitis

Diagnosis (autoantibodies + IgG + biopsy + simplified IAIHG score), corticosteroid + azathioprine, monitor for relapse.

BSG 2018; AASLD 2019
Primary Biliary Cholangitis / Primary Sclerosing Cholangitis

Differentiate PBC (AMA+, female, intrahepatic, UDCA-responsive) from PSC (M>F, IBD association, MRCP, no proven medical therapy).

EASL 2017 PBC; EASL 2022 PSC; BSG
Iron Overload (Haemochromatosis) / Wilson's Workup

Recognise hereditary iron overload (HFE C282Y) and Wilson's (low ceruloplasmin, urinary copper) — diagnostic workup and management.

BSG 2018; EASL 2022 Wilson; AASLD 2018 Haemochromatosis
Hepatocellular Carcinoma — Surveillance & Management

EASL 2018 / BSG — surveillance criteria, BCLC staging, treatment by stage (resection, ablation, TACE, systemic, transplant).

EASL 2018; BSG 2024; BCLC 2022