Local Anaesthetic Maximum Dose Calculator
Calculates maximum safe dose of common local anaesthetics to prevent systemic toxicity (LAST).
Score interpretation
Maximum dose <100 mg. Use with care — small margin for error.
→ Use dilute solution to increase volume. Aspirate before injection. Consider reduced dose in elderly or hepatic impairment. Have Intralipid 20% available.
Moderate maximum dose calculated.
→ Administer in fractionated doses with aspiration. Do not exceed calculated maximum. Monitor for signs of LAST (metallic taste, tinnitus, perioral tingling, cardiovascular collapse).
Larger maximum dose for higher weight patients.
→ Apply standard precautions: fractionate injection, aspirate, have Intralipid 20% immediately available.
Interpretation bands for the Local Anaesthetic Dose. Apply clinical judgement and local guidance.
References
- AAGBI Safety Guideline: Management of Severe Local Anaesthetic Toxicity. Association of Anaesthetists of Great Britain and Ireland. 2010.
- Neal JM et al. ASRA Practice Advisory on Local Anesthetic Systemic Toxicity. Reg Anesth Pain Med. 2018;43(2):113-123.
Related
Curated clinical cross-links plus same-class fallbacks.
- Bupivacaine · Local Anaesthetic (Amide)
- Lidocaine (IV — Anaesthesia/ICU) · Local Anaesthetic / Antiarrhythmic (Class Ib)
- Prilocaine · Local Anaesthetic (Amide)
- Lidocaine hydrochloride · Amide local anaesthetic / Class IB antiarrhythmic
- Bupivacaine hydrochloride · Long-acting amide local anaesthetic
- Chlorhexidine with lidocaine · Antiseptic with local anaesthetic
Decision support only — verify against a current formulary, NICE, or your local guideline before clinical use.