Chlorhexidine with lidocaine
A combined antiseptic and local anaesthetic lubricant gel of chlorhexidine with lidocaine, used for urethral catheterisation and instrumentation to disinfect and provide surface anaesthesia and lubrication.
ClinCalc Pro is rebuilding its dose data from primary open sources — the manufacturer SmPC (eMC), the WHO Model Formulary and other official references — under clinician review. This drug's structured dose is not yet published here. Confirm all doses against the product SmPC and your local formulary before prescribing.
Clinical monograph
How it works
Chlorhexidine disrupts microbial membranes to provide antisepsis, while lidocaine, an amide local anaesthetic, blocks neuronal sodium channels to reduce sensation in the mucosa it contacts.
Prescribing in practice
- Systemic absorption of lidocaine from the mucosa can occur, so excessive volumes and use on grossly traumatised urethral mucosa should be avoided to prevent local-anaesthetic toxicity, especially in frail or elderly patients.
- Avoid in known hypersensitivity to amide anaesthetics or chlorhexidine, and keep away from the eyes and middle ear.
- Use with caution where there is significant mucosal injury that could increase absorption.
Monitoring
Watch for early features of local-anaesthetic toxicity (perioral numbness, dizziness) when larger amounts are used or the mucosa is damaged.
Counselling the patient
- Some numbness in the area is expected and temporary.
- Tell the clinician about any allergy to local anaesthetics or antiseptics before the procedure.
Evidence & guidelines
Cautions on lidocaine absorption and amide-anaesthetic hypersensitivity reflect the SPC and standard procedural practice.
Reference: Drug verified in RxNorm (NLM); confirm dosing against the manufacturer SPC (eMC). Verify against your local formulary and current prescribing references before prescribing. Monograph status: clinician-reviewed (2026-07-04).
Related
Curated clinical cross-links plus same-class fallbacks.