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Cardiology Haematology Strong — Fang 2011 / ATRIA Study

ATRIA Bleeding Risk Score

Predicts major bleeding risk in patients with atrial fibrillation on warfarin anticoagulation. Complements HAS-BLED.

Used in: Atrial Fibrillation

Score interpretation

Low Bleeding Risk (~0.8%/year) 0–3

ATRIA 0–3: Low annual bleeding risk (~0.8%). Benefits of anticoagulation outweigh risks in AF.

→ Continue or initiate anticoagulation (DOAC preferred over warfarin). Annual review. Optimise modifiable bleeding risk factors (BP, anaemia, alcohol).

Intermediate Risk (~2.6%/year) 4

ATRIA 4: Intermediate annual bleeding risk (~2.6%). Reassess risk-benefit.

→ Discuss risk-benefit with patient. Treat modifiable risk factors. Ensure BP controlled. Avoid NSAIDs/aspirin combination. DOAC preferred. 6-monthly review.

High Bleeding Risk (~5.8%/year) 5–10

ATRIA ≥ 5: High annual bleeding risk (~5.8%). Weigh carefully against stroke risk (CHA₂DS₂-VASc).

→ Weigh ATRIA bleeding risk against CHA₂DS₂-VASc stroke risk. If CHA₂DS₂-VASc ≥ 2 (men) / ≥ 3 (women), anticoagulation still usually outweighs risk. Aggressively address modifiable factors. Consider PPI cover. Cardiology / anticoagulation clinic referral.

Interpretation bands for the ATRIA Bleeding. Apply clinical judgement and local guidance.

References

Related

Curated clinical cross-links plus same-class fallbacks.

📚 MRCEM Revision

Featured in these MRCEM clinical pathways

The ATRIA Bleeding is covered in detail — with RCEM/NICE evidence base, indications and pitfalls — in the following exam-focused pathways on our sister siteReviseMRCEM.

MRCEM Primary / Intermediate / OSCE candidates: each pathway includes exam-style questions, RCEM/NICE citations, and FAQ summaries.

Decision support only — verify against a current formulary, NICE, or your local guideline before clinical use.