Cardiology General Medicine
INTERCHEST Clinical Prediction Rule
Predicts probability of cardiac chest pain in primary care. Score ≥1 suggests cardiac cause.
Score interpretation
Low Probability — Non-Cardiac -1–0
INTERCHEST < 1: Low probability of cardiac chest pain. Musculoskeletal or other cause likely.
→ Reassure patient. Treat underlying non-cardiac cause.
High Probability — Cardiac 1–6
INTERCHEST ≥ 1: High probability of cardiac chest pain. Further cardiac evaluation warranted.
→ ECG, troponin, cardiology referral. Consider stress testing.
Interpretation bands for the INTERCHEST. Apply clinical judgement and local guidance.
References
- Haasenritter J et al. Chest pain in primary care: is the localization of pain diagnostically helpful in the critical evaluation of patients? A cross sectional study. BMC Fam Pract. 2012;13:84.
Related
Curated clinical cross-links plus same-class fallbacks.
Calculators
- HEART Score for Major Adverse Cardiac Events · Chest Pain
- EDACS — Emergency Department Assessment of Chest Pain · Chest Pain
- HEAR Score for Acute Chest Pain · Chest Pain
- ACTION ICU Score for Intensive Care in NSTEMI · Chest Pain
- Marburg Heart Score · Chest Pain
- Subtle Anterior STEMI Calculator (4-Variable) · Chest Pain
Drugs
- Lidocaine IV (Cardiac Arrhythmia) · Antiarrhythmic
- Protamine Sulphate (Heparin Reversal) · Heparin Reversal / Cardiac Surgery
- Mavacamten · Cardiac myosin inhibitor
- Methoxyflurane · Inhaled Analgesic — Acute Pain
- Digoxin · Cardiac Glycoside
- Fentanyl Transdermal Patch (Elderly Chronic Pain) · Opioid Analgesic — Transdermal Patch
Pathways
- Acute Heart Failure · ESC 2021 Heart Failure Guidelines; NICE NG106
- NSTEMI / Unstable Angina · ESC 2020 NSTEMI Guidelines; NICE NG185
- New-Onset Atrial Fibrillation · ESC 2020 AF Guidelines; NICE NG196
- Hypertensive Emergency · ESC/ESH 2018 Hypertension Guidelines; NICE NG136
- Bradycardia Management · Resuscitation Council UK ABCDE; ESC 2021 Pacing Guidelines
- Ventricular Tachycardia / Fibrillation · Resuscitation Council UK ACLS; ESC 2022 Ventricular Arrhythmia Guidelines
Decision support only — verify against a current formulary, NICE, or your local guideline before clinical use.