Haematology Anaesthesia / Critical Care General Medicine Strong — widely validated; endorsed by ASH and BSH guidelines
4Ts Score for Heparin-Induced Thrombocytopenia
Estimates the pre-test probability of heparin-induced thrombocytopenia (HIT) using 4 clinical criteria. Low score safely excludes HIT; intermediate/high requires laboratory confirmation.
References
- Lo GK, et al. Evaluation of pretest clinical score (4 T's) for the diagnosis of heparin-induced thrombocytopenia in two clinical settings. J Thromb Haemost. 2006;4(4):759–765.
- Cuker A, et al. American Society of Hematology 2018 guidelines for management of venous thromboembolism: heparin-induced thrombocytopenia. Blood Adv. 2018;2(22):3360–3392.
Related
Curated clinical cross-links plus same-class fallbacks.
Drugs
- Protamine Sulphate · Heparin Reversal Agent
- Unfractionated Heparin (ACS / PCI) · Anticoagulant / ACS / PCI
- Bivalirudin (PCI Anticoagulation) · Direct Thrombin Inhibitor / PCI
- Protamine Sulphate (Heparin Reversal) · Heparin Reversal / Cardiac Surgery
- Heparinoid · Topical heparin analogue
- Unfractionated Heparin (IV) · Anticoagulant — ACS / PE / Thrombus
Pathways
- Major Haemorrhage / Massive Transfusion · BCSH; RCOA; RCEM; RCS — BCSH Guidelines
- Anaemia Investigation · BSH / NICE
- Deep Vein Thrombosis Diagnosis and Treatment · NICE CG144 / NICE NG158
- Sickle Cell Crisis · BSH 2021 / BCSH
- Neutropenic Sepsis · NICE CG151 2012 / ESMO
- Anticoagulation Reversal · BSH 2016 / ESC
Decision support only — verify against MDCalc, NICE, or your local guideline before clinical use.