neurology emergency-medicine critical-care
Cerebral Perfusion Pressure (CPP)
Calculates cerebral perfusion pressure from mean arterial pressure and intracranial pressure. Target CPP 60-70 mmHg in TBI.
Score interpretation
Adequate CPP
→ Maintain MAP and ICP targets; continue monitoring
Low-normal CPP
→ Optimise MAP (vasopressors if needed); reduce ICP
Critically low CPP
→ Immediate intervention: MAP augmentation, ICP reduction (mannitol, hyperventilation, drainage)
Interpretation bands for the CPP. Apply clinical judgement and local guidance.
References
Related
Curated clinical cross-links plus same-class fallbacks.
Drugs
- Sodium hyaluronate · Ocular lubricant (hyaluronic acid)
- Dexamethasone (Paediatric) · Corticosteroid — Croup / Bacterial Meningitis / Post-Extubation Stridor / Cerebral Oedema
- Medical-Grade Honey (Manuka) · Topical Wound Care Agent
- Silicone Gel / Sheeting (Scar Management) · Medical Device / Topical Scar Treatment
Pathways
- Acute Stroke / TIA Assessment · NICE NG128; RCP Stroke Guidelines 2023
- Status Epilepticus (Adults) · NICE CG137; ESEM guidelines; RCP Neurology Guidelines
- Suspected Subarachnoid Haemorrhage · NICE NG228; RCEM 2023; AHA/ASA 2023
- Adult Head Injury · NICE NG232 (2023)
- Bell's Palsy / Facial Nerve Palsy · ENT UK 2017; AAN
- Vertigo Workup · ENT UK; NICE CKS
Decision support only — verify against a current formulary, NICE, or your local guideline before clinical use.