Chronic Kidney Disease
Also: CKD · renal impairment · kidney failure
Chronic kidney disease (CKD) is a long-term reduction in kidney function, staged by eGFR and albuminuria. Management focuses on slowing progression, cardiovascular risk, and safe medication dosing in renal impairment.
This hub gathers the eGFR/renal calculators, the renal drug-dosing tool, key drugs, and explainers.
Calculators & scores
- eGFR (CKD-EPI 2021)Renal Function
- CKD Staging (KDIGO 2012)Chronic Kidney Disease
- Schwartz Equation — Paediatric GFRRenal Function
- CKiD U25 eGFR Calculator for Children and Young AdultsRenal
- MDRD GFR EquationKidney Function
- CKD Staging by eGFR (KDIGO 2012)Diagnostic
- KDIGO Heat Map for CKD PrognosisChronic Kidney Disease
- Thakar Score for Acute Renal Failure after Cardiac SurgeryCardiac Surgery
- Mehran Score for Post-PCI Contrast NephropathyCoronary Artery Disease
- Thakar Score for AKI after Cardiac SurgerySurgical Risk
- PREVENT Cardiovascular Risk Calculator (AHA 2023)Cardiovascular Risk
- Creatinine Clearance (Cockcroft-Gault)Renal Function
- Fractional Excretion of Sodium (FENa)AKI
- Fractional Excretion of Urea (FeUrea)AKI
Decision pathways
- Acute Kidney Injury (AKI)KDIGO 2012 / NICE AKI 2019
- CKD-Mineral Bone Disease (CKD-MBD)KDIGO 2017 CKD-MBD
- Membranous NephropathyKDIGO 2021 GN
- CKD ManagementNICE CKD 2021 / KDIGO 2024
- RRT InitiationKDIGO 2012 / NICE
- Glomerulonephritis WorkupKDIGO 2021 GN; Renal Association
- Chronic Hyperkalaemia ManagementRenal Association 2020; NICE TAs
- Lupus NephritisEULAR/ERA-EDTA 2019; KDIGO 2024
Drugs
- Furosemide (IV — ICU)Loop Diuretic
- RamiprilAntihypertensive
- FurosemideDiuretic
- DapagliflozinSGLT2 Inhibitor
- Furosemide with triamtereneLoop diuretic + potassium-sparing
- Losartan potassiumAngiotensin II receptor antagonist (ARB)
- Losartan with hydrochlorothiazideARB + thiazide
- Ramipril with felodipineACE inhibitor + dihydropyridine CCB
- Spironolactone with furosemideK-sparing + loop diuretic combination
- Alfacalcidol (1-alpha-Hydroxycholecalciferol)Active Vitamin D Analogue
- Saxagliptin with dapagliflozinDPP-4 + SGLT2 inhibitor
- Dapagliflozin with metforminSGLT2i + biguanide (fixed-dose)
Patient explainers
Tools
Decision support only. These tools are aggregated by topic to aid navigation — always apply clinical judgement and the relevant national or local guideline.