Cardiology

Mehran Score for Post-PCI Contrast Nephropathy

Predicts risk of contrast-induced nephropathy (CIN) following percutaneous coronary intervention (PCI).

Score interpretation

Low Risk 0–5

Mehran 0–5: ~7.5% risk of contrast-induced nephropathy. <1% need for dialysis.

→ Standard IV hydration (NS 1 mL/kg/hr for 12h pre/post). Minimise contrast volume.

Moderate Risk 6–10

Mehran 6–10: ~14% risk of CIN. ~1.4% need for dialysis.

→ Aggressive hydration. Consider iso-osmolar contrast. Avoid NSAIDs/nephrotoxins.

High Risk 11–15

Mehran 11–15: ~26% risk of CIN. ~3.3% need for dialysis.

→ Maximum contrast minimisation. Renal protective strategy. Nephrology input.

Very High Risk 16–40

Mehran ≥ 16: ~57% risk of CIN. ~12.6% need for dialysis.

→ Consider alternative non-contrast imaging. Dialysis availability. Nephrology consult prior to procedure.

Interpretation bands for the Mehran Score. Apply clinical judgement and local guidance.

Mehran R et al. A simple risk score for prediction of contrast-induced nephropathy after percutaneous coronary intervention. J Am Coll Cardiol. 2004;44(7):1393-1399.

Curated clinical cross-links plus same-class fallbacks.

Calculators

Drugs

Pathways

Decision support only — verify against a current formulary, NICE, or your local guideline before clinical use.