ClinCalc Pro
Menu
ACE inhibitor + dihydropyridine CCB

Ramipril with felodipine

Brand names: Triapin

Adult dose

Dose: 2.5/2.5mg or 5/5mg PO OD
Route: PO
Frequency: OD

Clinical pearls

  • Hypertension when monotherapy inadequate
  • Per ACCOMPLISH-style combination

Contraindications

  • Pregnancy
  • Severe hypotension
  • Cardiogenic shock
  • Severe aortic stenosis

Side effects

  • Cough
  • Peripheral oedema
  • Headache
  • Hypotension
  • Hyperkalaemia

Interactions

  • NSAIDs
  • Strong CYP3A4 modulators
  • Lithium

Monitoring

  • U&E
  • BP

Reference: BNF; NICE NG136; https://bnf.nice.org.uk/drugs/ramipril-with-felodipine/. Verify against your local formulary and the latest BNF before prescribing.

Related

Curated clinical cross-links plus same-class fallbacks.