Topical otic corticosteroid + antiseptic

Flumetasone pivalate with clioquinol

Brand names: Locorten-Vioform

Flumetasone pivalate with clioquinol is a combined ear drop preparation of a topical corticosteroid and an anti-infective used in otitis externa with inflammation and infection.

Dosing — being independently re-sourced

ClinCalc Pro is rebuilding its dose data from primary open sources — the manufacturer SmPC (eMC), the WHO Model Formulary and other official references — under clinician review. This drug's structured dose is not yet published here. Confirm all doses against the product SmPC and your local formulary before prescribing.

Clinical monograph

How it works

Flumetasone pivalate is a corticosteroid that reduces local inflammation, while clioquinol provides antibacterial and antifungal activity in the ear canal.

Prescribing in practice

It should be avoided when the tympanic membrane is perforated unless specifically directed, as instillation into the middle ear is generally not recommended.
Clioquinol can stain skin and clothing, and may interfere with thyroid function tests.
As with other topical ear corticosteroid combinations, treatment is kept short-term.

Monitoring

Review the ear clinically for response and check the tympanic membrane status before and during treatment.

Counselling the patient

Use only in the affected ear as directed.
Be aware the drops may stain skin or clothing.
Return if symptoms do not improve or the ear becomes more painful.

Evidence & guidelines

Combined corticosteroid and anti-infective ear drops are an established treatment for inflamed, infected otitis externa in UK practice.

Reference: Drug verified in RxNorm (NLM); confirm dosing against the manufacturer SPC (eMC). Verify against your local formulary and current prescribing references before prescribing. Monograph status: clinician-reviewed (2026-07-04).

Curated clinical cross-links plus same-class fallbacks.

Calculators

Pathways