Topical otic corticosteroid + antiseptic

Flumetasone pivalate with clioquinol

Brand names: Locorten-Vioform

Flumetasone pivalate with clioquinol is a combined ear drop preparation of a topical corticosteroid and an anti-infective used in otitis externa with inflammation and infection.

Dosing — no UK product information found

We found no UK product information (SmPC) for this medicine or presentation on the eMC or MHRA Products (checked October 2026). It may be unlicensed in the UK, imported, a medical device, or no longer marketed. ClinCalc Pro shows only doses it can trace to official product information, so none is shown — follow your specialist service or local guideline.

Clinical monograph

How it works

Flumetasone pivalate is a corticosteroid that reduces local inflammation, while clioquinol provides antibacterial and antifungal activity in the ear canal.

Prescribing in practice

It should be avoided when the tympanic membrane is perforated unless specifically directed, as instillation into the middle ear is generally not recommended.
Clioquinol can stain skin and clothing, and may interfere with thyroid function tests.
As with other topical ear corticosteroid combinations, treatment is kept short-term.

Monitoring

Review the ear clinically for response and check the tympanic membrane status before and during treatment.

Counselling the patient

Use only in the affected ear as directed.
Be aware the drops may stain skin or clothing.
Return if symptoms do not improve or the ear becomes more painful.

Evidence & guidelines

Combined corticosteroid and anti-infective ear drops are an established treatment for inflamed, infected otitis externa in UK practice.

Reference: Drug verified in RxNorm (NLM); confirm dosing against the manufacturer SPC (eMC). Verify against your local formulary and current prescribing references before prescribing. Monograph status: clinician-reviewed (2026-07-04).

Curated clinical cross-links plus same-class fallbacks.

Calculators

Pathways