Zinc sulfate

SCOPE — ORAL ZINC SUPPLEMENTATION ONLY. That is this page's primary use (page category 'Zinc supplement'), and it is what this SPC doses. The SPC states no regimen for Wilson's disease (this page already defers that to zinc acetate) and no regimen for any other indication. STRENGTH CAVEAT — READ BEFORE TRANSPOSING: the §4.2 posology contains no milligram figure at all; it doses in whole tablets. The only strength anywhere in the bundle is the product name itself, 'Solvazinc 45mg Effervescent Tablets.', and no §2 qualitative composition was fetched — so this source does not establish whether that 45 mg denotes elemental zinc or zinc sulfate salt (the strings 'elemental' and '125' appear nowhere in the bundle). The regimen above is therefore valid for the named 45 mg effervescent tablet only: do not convert it into milligrams of zinc, and do not apply it to another zinc sulfate presentation — this page's other listed brand, Z Span Spansule, is a different (modified-release) presentation and is not covered by this SPC. DURATION — §4.4 verbatim: 'Therapy should continue until clinical improvement occurs and Solvazinc can be replaced by dietary measures unless there is severe malabsorption, metabolic disease or continuing zinc loss. Continued long-term treatment with Solvazinc if zinc deficiency is no longer present may lead to copper deficiency.' ADMINISTRATION SPACING — §4.5 verbatim: 'Zinc may reduce the absorption of concurrently administered tetracyclines, also the absorption of zinc may be reduced by tetracyclines; when both are being given an interval of at least three hours should be allowed.' §4.5 also records mutual absorption interference with oral iron, penicillamine and trientine; reduced absorption of quinolones (ciprofloxacin, levofloxacin, moxifloxacin, norfloxacin, ofloxacin); reduced absorption of zinc with calcium salts; and inhibition of copper absorption by zinc. EXCIPIENTS — §4.4 verbatim: 'This product contains sorbitol (E420), therefore patients with rare hereditary problems of fructose intolerance should not take this medicine' and 'This medicinal product contains 106mg sodium per tablet, equivalent to 5.3% of the WHO recommended maximum daily intake of 2g sodium for an adult.' FLAGGED FOR THE REVIEWER — the existing page text contradicts itself on the salt-versus-elemental question: its dose line reads '45mg elemental zinc 1–3 times daily' while its clinical pearls read 'zinc sulfate 45mg ≈ 10mg elemental zinc'. Neither statement is supported by anything in this bundle; both should be resolved against SPC §2 before publication.

WEIGHT-BANDED BY TABLET FRACTION, NOT PER KILOGRAM — dosePerKg is null because §4.2 doses children by weight band in whole and half tablets and gives no mg/kg figure at any age; no weight-calculator figure applies and no per-kilogram dose may be derived from these bands. concentration is null because an effervescent tablet has no milligrams-per-millilitre strength. §4.2 verbatim: 'Children: More than 30kg: One tablet, dissolved in water, once to three times daily after meals. 10-30kg: ½ tablet, dissolved in water, once to three times daily after meals. Less than 10kg: ½ tablet, dissolved in water, once daily after meals.' (the fetched text renders each half as the HTML entity '½', i.e. ½). The adult strength caveat applies unchanged: the bands are whole and half tablets of Solvazinc 45mg Effervescent Tablets, and this source does not establish the milligram content of a tablet, so they cannot be converted to milligrams or to another product. Verify all paediatric zinc dosing against a children's formulary before prescribing.