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Combined oral contraceptive

Ethinylestradiol with norgestimate

Brand names: Cilique, Lizinna

Adult dose

Dose: 1 tablet OD per pack regimen
Route: Oral
Frequency: OD

Clinical pearls

  • Norgestimate metabolised partly to levonorgestrel — VTE profile considered closer to 2nd-generation
  • FSRH UKMEC eligibility

Contraindications

  • Standard CHC contraindications

Side effects

  • Breakthrough bleeding
  • Headache
  • VTE
  • Breast tenderness
  • Mood change

Interactions

  • Enzyme inducers
  • Lamotrigine

Monitoring

  • BP
  • Migraine status
  • BMI

Reference: BNF; FSRH CHC guideline; UKMEC; https://bnf.nice.org.uk/drugs/ethinylestradiol-with-norgestimate/. Verify against your local formulary and the latest BNF before prescribing.

Related

Curated clinical cross-links plus same-class fallbacks.