Recombinant FSH
Follitropin alfa
Brand names: Gonal-F, Bemfola, Ovaleap
Adult dose
Dose: Per stimulation protocol — typically 75–225 units SC OD
Route: SC
Frequency: OD
Clinical pearls
- Anovulation, controlled ovarian stimulation in IVF/ART
- Specialist fertility unit
Contraindications
- Hormone-dependent tumours
- Tumours of pituitary/hypothalamus
- Pregnancy
- Ovarian/uterine malformation incompatible with pregnancy
Side effects
- OHSS
- Local reactions
- Multiple pregnancy
- Headache
Monitoring
- Ultrasound
- Oestradiol
Reference: BNF; NICE CG156; https://bnf.nice.org.uk/drugs/follitropin-alfa/. Verify against your local formulary and the latest BNF before prescribing.
Related
Curated clinical cross-links plus same-class fallbacks.
Pathways
- Spinal Anaesthesia Hypotension Management · AAGBI; ASA
- Pre-Eclampsia / Eclampsia in ED · NICE NG133; RCOG Green-top 10A
- Suspected Ectopic Pregnancy · NICE NG126; RCOG Green-top 21
- Polycystic Ovary Syndrome (PCOS) · International PCOS Guideline 2023; NICE CKS
- Pre-eclampsia Management · NICE NG133 2019
- Ectopic Pregnancy · NICE CG154 / RCOG GTG 21