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Urinary FSH

Urofollitropin

Brand names: Fostimon

Urofollitropin is a urinary-derived preparation of follicle-stimulating hormone (FSH) used in assisted reproduction to stimulate ovarian follicular development, including ovulation induction and controlled ovarian stimulation for IVF.

Dosing — being independently re-sourced

ClinCalc Pro is rebuilding its dose data from primary open sources — the manufacturer SmPC (eMC), the WHO Model Formulary and other official references — under clinician review. This drug's structured dose is not yet published here. Confirm all doses against the product SmPC and your local formulary before prescribing.

Clinical monograph

How it works

It provides exogenous FSH that acts on ovarian granulosa cells to promote the growth and maturation of ovarian follicles.

Prescribing in practice

  • It can cause ovarian hyperstimulation syndrome and multiple pregnancy, so treatment must be supervised by a specialist with ultrasound and hormonal monitoring of the ovarian response.
  • Treatment should be individualised and stopped or adjusted if there is an excessive ovarian response.
  • Thromboembolic events can occur, particularly in the context of ovarian hyperstimulation syndrome.

Monitoring

Monitor follicular development with serial ultrasound and oestradiol measurement to guide dosing and reduce the risk of hyperstimulation.

Counselling the patient

  • This medicine stimulates the ovaries and requires regular scans and blood tests.
  • Report severe abdominal pain, bloating, breathlessness, or reduced urine output promptly as these may indicate overstimulation.
  • Be aware that treatment increases the chance of a multiple pregnancy.

Evidence & guidelines

An established gonadotrophin used in specialist-supervised fertility treatment, consistent with current prescribing references.

Reference: NICE CG156; Drug verified in RxNorm (NLM); confirm dosing against the manufacturer SPC (eMC). Verify against your local formulary and current prescribing references before prescribing. Monograph status: clinician-reviewed (2026-07-04).

Related

Curated clinical cross-links plus same-class fallbacks.

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