Topical ophthalmic combination (steroid + aminoglycoside + polypeptide)
Dexamethasone with hypromellose, neomycin and polymyxin B sulfate
Brand names: Maxitrol
Adult dose
Dose: 1–2 drops 4–6× daily; ointment QDS
Route: Ophthalmic
Frequency: QDS+
Clinical pearls
- RCOphth: short-course post-cataract / inflammatory ophthalmology with bacterial cover
- Specialist ophthalmology supervision for >2-week courses (IOP risk)
Contraindications
- Viral / fungal / tuberculous eye infection
- Glaucoma
- Aminoglycoside hypersensitivity
Side effects
- Stinging
- Burning
- Increased IOP
- Cataract (prolonged use)
- Corneal thinning
- Superinfection
Interactions
- Other ototoxic / nephrotoxic drugs (theoretical)
Monitoring
- IOP
- Visual acuity
- Symptom resolution
Reference: BNF; RCOphth; https://bnf.nice.org.uk/drugs/dexamethasone-with-hypromellose-neomycin-and-polymyxin-b-sulfate/. Verify against your local formulary and the latest BNF before prescribing.
Related
Curated clinical cross-links plus same-class fallbacks.
Calculators
- Steroid Dose Equivalence · Medications
- Adrenal Crisis Risk Score · Adrenal Disorders
- Ideal Body Weight (Devine) · Anthropometry
- Lille Model (Steroid Response in Alcoholic Hepatitis) · Alcoholic Liver Disease
- Ho Index for Predicting Response to Medical Therapy in IBD · Inflammatory Bowel Disease
- Apfel Score for Postoperative Nausea and Vomiting · Perioperative
Pathways
- Acute Red Eye / Vision Loss Screen · RCOphth 2020; NICE CKS
- Idiopathic Intracranial Hypertension · ABN; consensus 2018
- Acute Red Eye Assessment · RCOphth / AAO
- Acute Angle Closure Glaucoma · RCOphth / EGS Guidelines
- Retinal Detachment · RCOphth Guidelines / EURETINA
- Diabetic Retinopathy — Screening and Management · NICE NG28 2016 / NHS DES Programme