Dexamethasone 0.1% Eye Drops (Maxidex)

How it works

Dexamethasone binds glucocorticoid receptors to suppress the inflammatory cascade, reducing leucocyte infiltration, vascular permeability and release of inflammatory mediators.

Prescribing in practice

• Topical ocular corticosteroids can raise intraocular pressure and promote cataract formation with prolonged use, and may worsen or mask ocular infection, so they should be used under ophthalmic supervision.
• They are contraindicated in untreated infective conditions such as herpes simplex keratitis (dendritic ulcer) and most acute purulent eye infections.
• Treatment should generally be tapered rather than stopped abruptly after prolonged courses to avoid rebound inflammation.

Monitoring

Monitor intraocular pressure during prolonged use and review the eye for evidence of infection or lens changes.

Counselling the patient

• Use the drops exactly as prescribed and do not extend the course without ophthalmic review.
• Report any eye pain, reduced vision or worsening redness promptly.
• Attend follow-up appointments so eye pressure can be checked.

Evidence & guidelines

Topical corticosteroids are standard therapy for steroid-responsive ocular inflammation, with use guided by the SPC and ophthalmic practice.