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Ocular lubricant (viscous eye drop — dry eye disease) Pregnancy: Compatible — topical use only; no systemic absorption.

Sodium Hyaluronate 0.1% Eye Drops (Hylo-Forte)

Brand names: Hylo-Forte, Hylo-Tear, Artelac Rebalance, Clinitas

Adult dose

Dose: 1 drop in each affected eye, 3–5 times daily or as required
Route: Ophthalmic
Frequency: 3–5 times daily (or more frequently in severe dry eye)
Max: No defined maximum — use as frequently as needed
Dry eye disease (DED): 1 drop 3–5 times daily. Hylo-Forte 0.2% for more severe symptoms. Preservative-free formulations preferred for frequent use (>4 times/day) and contact lens wearers. Can be used with contact lenses in situ (preservative-free). Hylo products use COMOD multidose preservative-free delivery system.

Paediatric dose

Route: Ophthalmic
Frequency: As required
Max: As required
Safe for use in children. No specific paediatric dosing — apply 1 drop as needed. Useful post-operatively and for dry eye secondary to systemic conditions.

Dose adjustments

Renal

No adjustment required.

Hepatic

No adjustment required.

Clinical pearls

  • Preservative-free is strongly preferred for dry eye — benzalkonium chloride (BAK) in preserved drops worsens dry eye disease over time
  • Higher molecular weight hyaluronate gives longer retention time on ocular surface
  • Viscous drops (e.g., 0.2%) suited for severe dry eye; thicker gels (carbomer) better for nocturnal use
  • Contact lens wearers can insert without removing lenses if preservative-free
  • DEWS II guidelines recommend a step-up approach: if artificial tears alone insufficient, consider omega-3 supplementation, serum eye drops, or cyclosporine

Contraindications

  • Hypersensitivity to sodium hyaluronate or any excipient

Side effects

  • Transient blurred vision on instillation (clears with blinking)
  • Eyelid stickiness (rare)
  • Hypersensitivity reactions (rare)

Interactions

  • No clinically significant interactions

Monitoring

  • Symptom response (OSDI score)
  • Corneal staining (fluorescein/rose bengal) at specialist review

Reference: BNFc; BNF; DEWS II Report 2017; NICE guidance Dry Eye; Hylo-Forte SPC. Verify against your local formulary and the latest BNF before prescribing.

Related

Curated clinical cross-links plus same-class fallbacks.

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