Mehran Score for Post-PCI Contrast Nephropathy
Predicts risk of contrast-induced nephropathy (CIN) following percutaneous coronary intervention (PCI).
Score interpretation
Mehran ≤ 5: contrast-induced nephropathy 7.5 %; dialysis 0.04 %.
→ Standard IV hydration (NS 1 mL/kg/hr for 12h pre/post). Minimise contrast volume.
Mehran 6–10: contrast-induced nephropathy 14.0 %; dialysis 0.12 %.
→ Aggressive hydration. Consider iso-osmolar contrast. Avoid NSAIDs/nephrotoxins.
Mehran 11–15: contrast-induced nephropathy 26.1 %; dialysis 1.09 %.
→ Maximum contrast minimisation. Renal protective strategy. Nephrology input.
Mehran ≥ 16: contrast-induced nephropathy 57.3 %; dialysis 12.6 %.
→ Consider alternative non-contrast imaging. Dialysis availability. Nephrology consult prior to procedure.
Interpretation bands for the Mehran Score. Apply clinical judgement and local guidance.
References
- Mehran R et al. A simple risk score for prediction of contrast-induced nephropathy after percutaneous coronary intervention. J Am Coll Cardiol. 2004;44(7):1393-1399.
Related
Curated clinical cross-links plus same-class fallbacks.
- DAPT Score · Coronary Artery Disease
- Canadian Cardiovascular Society (CCS) Angina Grading · Coronary Artery Disease
- Duke Treadmill Score · Coronary Artery Disease
- ARC-HBR Criteria for High Bleeding Risk in PCI · Coronary Artery Disease
- PRECISE-DAPT Score for Bleeding on DAPT · Coronary Artery Disease
- SYNTAX Score for Coronary Artery Disease · Coronary Artery Disease
- Colchicine (Pericarditis / Post-MI Inflammation) · Pericarditis / Coronary Inflammation
- N-Acetylcysteine (Contrast Nephropathy) · Contrast-Induced Nephropathy Prevention
- Lisinopril (HFrEF / Post-MI) · ACE Inhibitor / HFrEF
- Clopidogrel (ACS / Post-PCI) · Antiplatelet / ACS
- Methotrexate (Dermatology — Psoriasis) · Disease-Modifying Antirheumatic / Immunosuppressant
- Acetazolamide (Ménière's Disease) · Carbonic Anhydrase Inhibitor (Diuretic)
- Acute Heart Failure · ESC 2021 Heart Failure Guidelines; NICE NG106
- NSTEMI / Unstable Angina · ESC 2020 NSTEMI Guidelines; NICE NG185
- New-Onset Atrial Fibrillation · ESC 2020 AF Guidelines; NICE NG196
- Hypertensive Emergency · ESC/ESH 2018 Hypertension Guidelines; NICE NG136
- Bradycardia Management · Resuscitation Council UK ABCDE; ESC 2021 Pacing Guidelines
- Ventricular Tachycardia / Fibrillation · Resuscitation Council UK ACLS; ESC 2022 Ventricular Arrhythmia Guidelines
Decision support only — verify against a current formulary, NICE, or your local guideline before clinical use.