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Potassium binder

Patiromer calcium

Brand names: Veltassa

Adult dose

Dose: Initial 8.4g OD; titrate weekly to max 25.2g OD
Route: PO
Frequency: OD

Clinical pearls

  • Chronic hyperkalaemia in CKD/HF on RAASi to enable dose optimisation
  • NICE TA1064 supports use

Contraindications

  • Bowel obstruction
  • Hypersensitivity

Side effects

  • Constipation
  • Hypomagnesaemia
  • Hypocalcaemia (mild)
  • Diarrhoea
  • Abdominal pain

Interactions

  • Many — separate from other oral drugs by ≥3h before or after
  • Levothyroxine, ciprofloxacin, metformin, mycophenolate

Monitoring

  • K+
  • Mg2+
  • U&E

Reference: BNF; NICE TA1064; SmPC; https://bnf.nice.org.uk/drugs/patiromer-calcium/. Verify against your local formulary and the latest BNF before prescribing.

Related

Curated clinical cross-links plus same-class fallbacks.