Flavoxate hydrochloride
Brand names: Urispas
Flavoxate hydrochloride is a smooth-muscle relaxant used to relieve urinary frequency, urgency, dysuria and bladder spasm associated with conditions such as cystitis and lower urinary tract inflammation.
ClinCalc Pro is rebuilding its dose data from primary open sources — the manufacturer SmPC (eMC), the WHO Model Formulary and other official references — under clinician review. This drug's structured dose is not yet published here. Confirm all doses against the product SmPC and your local formulary before prescribing.
Clinical monograph
How it works
It exerts a direct antispasmodic action on urinary tract smooth muscle, with antimuscarinic and local anaesthetic properties, reducing detrusor overactivity.
Prescribing in practice
- It is contraindicated in gastrointestinal or urinary tract obstruction and should be avoided where antimuscarinic effects are hazardous, such as glaucoma.
- Anticholinergic effects including dry mouth, blurred vision and drowsiness may occur.
- It does not treat the underlying cause of infection, so appropriate investigation and treatment of any infection are still required.
Monitoring
Monitor symptomatic response and anticholinergic adverse effects, ensuring any underlying urinary infection is treated appropriately.
Counselling the patient
- This medicine eases bladder discomfort but does not replace treatment of any infection.
- It may cause drowsiness or blurred vision; take care with driving and skilled tasks.
- Report difficulty passing urine or worsening symptoms.
Evidence & guidelines
Flavoxate is an established symptomatic treatment for lower urinary tract spasm, used in line with the current prescribing references.
Reference: NICE NG123; Drug verified in RxNorm (NLM); confirm dosing against the manufacturer SPC (eMC). Verify against your local formulary and current prescribing references before prescribing. Monograph status: clinician-reviewed (2026-07-04).
Related
Curated clinical cross-links plus same-class fallbacks.