Haematology
Lymphoma Diagnostic Pathway
B-symptoms, staging (Ann Arbor / Lugano), excisional biopsy, staging investigations, MDT, treatment by type/stage.
Source: BSH 2024; NICE NG52
Step 1 of ~7
info
Suspect — Lymphadenopathy + Symptoms
Persistent (>4 weeks) painless lymphadenopathy ± B symptoms (fever >38°C, drenching night sweats, unexplained weight loss >10% in 6 months) ± hepatosplenomegaly ± fatigue / pruritus / SVCO. Painful node with alcohol = classical Hodgkin's. NICE 2WW referral criteria for suspected lymphoma — unexplained lymphadenopathy +/- B-symptoms, mediastinal/abdominal mass.
Related
Curated clinical cross-links plus same-class fallbacks.
Drugs
- Methylene Blue · Guanylate Cyclase / Nitric Oxide Pathway Inhibitor
- Thiamine (IV/IM — Pabrinex) · Vitamin B1 (Thiamine) — deficiency treatment / Wernicke's encephalopathy prevention
- Dextrose 10% IV · IV glucose solution (hypoglycaemia treatment)
- Glucose · Carbohydrate / hypoglycaemia treatment
- Medroxyprogesterone Acetate (DMPA) · Injectable Progestogen Contraceptive / Hormone Treatment
- Tirzepatide · Dual GIP/GLP-1 Receptor Agonist — Type 2 Diabetes / Obesity
Pathways
- Major Haemorrhage / Massive Transfusion · BCSH; RCOA; RCEM; RCS — BCSH Guidelines
- Anaemia Investigation · BSH / NICE
- Splenomegaly Workup · BSH; BMJ Best Practice
- Deep Vein Thrombosis Diagnosis and Treatment · NICE CG144 / NICE NG158
- Sickle Cell Crisis · BSH 2021 / BCSH
- Neutropenic Sepsis · NICE CG151 2012 / ESMO
Decision support only. Always apply local guidelines and clinical judgement.