SurgeryInfectious Disease
Surgical Site Infection
NICE NG125 — prevention bundle, classify (superficial/deep/organ-space), antibiotic stewardship, source control.
Source: NICE NG125 (2019)
Step 1 of ~3
info
Classify
CDC classification (within 30 days of surgery, 90 days if implant):
• Superficial: skin + subcutaneous tissue.
• Deep: fascia + muscle.
• Organ / space: deeper structures (e.g. abdominal abscess after laparotomy).
Diagnosis: erythema, swelling, pain, discharge, dehiscence, fever, raised inflammatory markers.
Imaging (USS / CT) for organ-space SSI.
Related
Curated clinical cross-links plus same-class fallbacks.
Drugs
- Flucloxacillin (Burns — Wound Infection) · Antibiotic — Penicillinase-Resistant Penicillin
- Colistin (Polymyxin E — XDR Burns Infection) · Antibiotic — Polymyxin (Last-Resort)
- Cefazolin (Surgical Prophylaxis) · 1st Generation Cephalosporin (Surgical Antibiotic Prophylaxis)
- Clindamycin (Surgical Prophylaxis — Penicillin Allergy) · Antibiotic (Lincosamide) — Surgical Prophylaxis
- Teicoplanin (Surgical Prophylaxis/MRSA) · Glycopeptide Antibiotic
- Tranexamic Acid (ICU/Trauma/Surgical) · Antifibrinolytic
Pathways
- Major Trauma — Primary Survey (ATLS) · ATLS 10th Edition; JRCALC; NICE NG39
- Major Haemorrhage / Massive Transfusion · BCSH; RCOA; RCEM; RCS — BCSH Guidelines
- Burns — TBSA Estimation & Fluid Resuscitation · British Burn Association; EMSB; RCEM 2024
- Lower Gastrointestinal Bleed · NICE; BSG; ACPGBI — Commissioning Guide
- Acute Pancreatitis · NICE; IAP/APA; ACPGBI — CG104
- Hypertrophic Pyloric Stenosis · BAPS / RCPCH
Decision support only. Always apply local guidelines and clinical judgement.