general-medicine geriatrics
CRASH Score — Chemotherapy Risk Assessment Scale for High-Age
Stratifies risk of severe chemotherapy toxicity in adults ≥70 (Extermann 2012). Combines patient factors (haemoglobin, creatinine clearance, IADL, MMSE/MNA, ECOG, LDH) + chemotherapy regimen toxicity. Use the band closest to your calculated score.
References
Related
Curated clinical cross-links plus same-class fallbacks.
Calculators
Drugs
- Palivizumab · RSV Prophylaxis — Monthly Monoclonal Antibody (High-Risk Infants)
- Hydroxocobalamin (High-Dose — Cyanide Antidote) · Cyanide Antidote (Vitamin B12 Precursor at High Dose)
- Thiamine (IV/IM — Pabrinex) · Vitamin B1 (Thiamine) — deficiency treatment / Wernicke's encephalopathy prevention
- Folinic Acid (Calcium Folinate / Leucovorin) · Antidote / Chemotherapy Support
- Calcium chloride · IV calcium salt (high elemental calcium)
- Zoledronic Acid · Bisphosphonate (IV)
Pathways
- Falls Assessment in Older Adults · NICE CG161 2013
- Anaemia Investigation · BSH / NICE
- Lower Respiratory Tract Infection (Primary Care) · NICE NG138 / NICE antimicrobial guidance
- Hypertension Management · NICE NG136 2019
- Delirium Outside ICU · NICE CG103
- Comprehensive Geriatric Assessment (CGA) · BGS / NICE
Decision support only — verify against MDCalc, NICE, or your local guideline before clinical use.