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General Medicine Haematology Strong — NICE NG89 Recommended

Padua Prediction Score (VTE Risk)

Assesses VTE risk in medical inpatients to guide pharmacological thromboprophylaxis.

Used in: Venous Thromboembolism (DVT & PE)

Metastatic or locally advanced; chemo/radiotherapy in past 6 months

Excluding superficial thrombophlebitis

Bed rest ≥3 days (not related to surgery)

AT III, PC/PS deficiency, Factor V Leiden, APLS, etc.

How to use & interpret

The Padua Prediction Score estimates venous thromboembolism risk in hospitalised medical (non-surgical) patients to guide pharmacological thromboprophylaxis. Points are weighted across factors such as active cancer, previous VTE, reduced mobility, known thrombophilia, recent trauma/surgery, age ≥70, heart/respiratory failure, acute MI/stroke, infection/rheumatological disease, obesity and hormone therapy.

A score of ≥4 indicates high risk, where prophylaxis (e.g. LMWH) is recommended unless bleeding risk contraindicates it. Always weigh it against bleeding risk and local policy.

Score interpretation

Low Risk 0–3

Score 0–3: Low VTE risk. 0.3% VTE rate without prophylaxis.

→ Mechanical prophylaxis (compression stockings/IPC). Ensure adequate hydration and early mobilisation.

High Risk 4–20

Score ≥4: High VTE risk. 11% VTE rate without prophylaxis.

→ Pharmacological thromboprophylaxis: LMWH (enoxaparin 40mg SC OD; renally adjust if eGFR < 30). Also mechanical prophylaxis.

Interpretation bands for the Padua VTE. Apply clinical judgement and local guidance.

Frequently asked questions

Padua or Caprini?

Padua is validated for medical inpatients; Caprini is designed for surgical patients. Use the one matching your patient group.

References

Related

Curated clinical cross-links plus same-class fallbacks.

Decision support only — verify against a current formulary, NICE, or your local guideline before clinical use.