haematology infectious-disease
4C Mortality Score for COVID-19
Validated prognostic score predicting in-hospital mortality in adults hospitalised with COVID-19. Uses 8 readily available clinical variables at admission. Validated in multiple national and international cohorts.
References
- Knight SR et al. Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score. BMJ. 2020;370:m3339.
- NICE COVID-19 rapid guideline: managing COVID-19. NICE NG191. 2021 (updated 2023).
Related
Curated clinical cross-links plus same-class fallbacks.
Drugs
- Dexamethasone (ICU / ARDS) · Systemic Corticosteroid
- Tocilizumab (ICU — Cytokine Storm / COVID-19) · IL-6 Receptor Inhibitor
- Dexamethasone · Potent Systemic Corticosteroid
- Acetic Acid 2% (Ear Drops) · Topical antibacterial / Antifungal (ear)
- Dexamethasone · Corticosteroid — ENT Inflammation / Croup
- Framycetin / Sofradex · Topical Antibiotic-Steroid — Otitis Externa
Pathways
- Major Haemorrhage / Massive Transfusion · BCSH; RCOA; RCEM; RCS — BCSH Guidelines
- Anaemia Investigation · BSH / NICE
- Splenomegaly Workup · BSH; BMJ Best Practice
- Deep Vein Thrombosis Diagnosis and Treatment · NICE CG144 / NICE NG158
- Sickle Cell Crisis · BSH 2021 / BCSH
- Neutropenic Sepsis · NICE CG151 2012 / ESMO
Decision support only — verify against MDCalc, NICE, or your local guideline before clinical use.