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Topical antibacterial / Antifungal (ear)

Acetic Acid 2% (Ear Drops)

Brand names: EarCalm, Otomize (with neomycin/dexamethasone)

Acetic acid ear drops are a topical preparation used to treat infections of the outer ear canal (otitis externa). The acidic preparation restores the normal acidity of the ear canal and has antibacterial and antifungal activity.

Dosing — being independently re-sourced

ClinCalc Pro is rebuilding its dose data from primary open sources — the manufacturer SmPC (eMC), the WHO Model Formulary and other official references — under clinician review. This drug's structured dose is not yet published here. Confirm all doses against the product SmPC and your local formulary before prescribing.

Clinical monograph

How it works

Acetic acid lowers the pH of the ear canal, creating an acidic environment that inhibits the growth of bacteria and fungi commonly responsible for otitis externa.

Prescribing in practice

  • It should not be used if the eardrum is known or suspected to be perforated, and treatment should be reviewed if symptoms do not improve, to reconsider the diagnosis.
  • It may cause transient stinging or burning in the ear on application.
  • It is intended for short-term topical use in the external ear canal only.

Monitoring

Review clinical response over the course of treatment and reassess if symptoms persist, worsen, or fail to settle within the expected period.

Counselling the patient

  • Use the drops in the affected ear as directed and avoid getting water in the ear.
  • A brief stinging sensation after putting the drops in is common and usually settles.
  • See your clinician if the ear does not improve, becomes more painful, or starts to discharge.

Evidence & guidelines

Topical acidifying preparations are a long-established treatment for otitis externa, supported by clinical practice and guidance for ear canal infections.

Reference: NICE NG91 Otitis Externa; SIGN 66; Drug verified in RxNorm (NLM); confirm dosing against the manufacturer SPC (eMC). Verify against your local formulary and current prescribing references before prescribing. Monograph status: clinician-reviewed (2026-07-04).

Related

Curated clinical cross-links plus same-class fallbacks.