Contrast Nephropathy Risk Score
Mehran risk score for contrast-induced acute kidney injury (CI-AKI) after contrast exposure.
Score interpretation
Score ≤5: CI-AKI risk ~7.5%
→ Standard IV hydration (0.9% saline or sodium bicarbonate); avoid nephrotoxins 24h before/after
Score 6–10: CI-AKI risk ~14%
→ IV hydration 1 mL/kg/h 12h before and after; use lowest contrast dose; consider iso-osmolar contrast; hold metformin
Score 11–15: CI-AKI risk ~26%
→ Pre-procedural hydration; consider N-acetylcysteine; hold nephrotoxins; nephrology input; post-procedure renal function at 48–72h
Score ≥16: CI-AKI risk ~57%; dialysis risk ~13%
→ Consider alternative imaging (MRI, USS); if mandatory: haemodialysis stand-by; minimise contrast; aggressive hydration
Interpretation bands for the Contrast Nephropathy. Apply clinical judgement and local guidance.
References
- Mehran R, et al. A simple risk score for prediction of contrast-induced nephropathy after percutaneous coronary intervention. J Am Coll Cardiol. 2004;44(7):1393-1399.
Related
Curated clinical cross-links plus same-class fallbacks.
- N-Acetylcysteine (Contrast Nephropathy) · Contrast-Induced Nephropathy Prevention
- Amoxicillin (Otitis Media / Sinusitis) · Beta-lactam antibiotic
- Palivizumab · RSV Prophylaxis — Monthly Monoclonal Antibody (High-Risk Infants)
- Sucralfate (Burns — GI Mucosal Protection) · Cytoprotective Agent — GI Mucosal Protection
- Ziprasidone · Atypical Antipsychotic — D2/5-HT2A Antagonist (Low Metabolic Risk)
- Vancomycin (Renal Dosing) · Antibiotic Dosing in CKD
Decision support only — verify against a current formulary, NICE, or your local guideline before clinical use.