Urology B

PSA Density Calculator

PSA Density = PSA / Prostate Volume (from TRUS). Helps differentiate benign BPH from prostate cancer.

Score interpretation

Low Density — BPH Likely 0–0.09

PSA density <0.10 ng/mL/mL: More likely benign BPH

→ Continued surveillance; PSA monitoring; no immediate biopsy required if other features benign

Borderline — Consider Biopsy 0.1–0.14

PSA density 0.10–0.14: Borderline zone

→ MRI prostate first (mpMRI); biopsy based on clinical picture and MRI result

High Density — Cancer Suspected ≥ 0.15

PSA density ≥0.15 ng/mL/mL: Increased risk of prostate cancer

→ Urgent mpMRI; urology referral; TRUS-guided or fusion biopsy recommended

Interpretation bands for the PSA Density. Apply clinical judgement and local guidance.

Benson MC, et al. Prostate specific antigen density: a means of distinguishing benign prostatic hypertrophy and prostate cancer. J Urol. 1992;147(3 Pt 2):815-816.

Curated clinical cross-links plus same-class fallbacks.

Calculators

Drugs

Pathways

Decision support only — verify against a current formulary, NICE, or your local guideline before clinical use.