Non-sedating H1 antihistamine
Loratadine
Brand names: Clarityn
Adult dose
Dose: 10mg OD
Route: PO
Frequency: OD
Paediatric dose
Route: PO
Frequency: OD
Age bands
- 24–72m: 5mg OD
- 72–216m: 10mg OD (>30 kg) or 5mg OD (≤30 kg)
Clinical pearls
- Allergic rhinitis, urticaria; first-line OTC non-sedating antihistamine
Contraindications
- Hypersensitivity
Side effects
- Headache
- Drowsiness (rare)
- Dry mouth
Interactions
- Strong CYP3A4 inhibitors (raised levels)
Reference: BNFc; BNF; BSACI; https://bnf.nice.org.uk/drugs/loratadine/. Verify against your local formulary and the latest BNF before prescribing.
Related
Curated clinical cross-links plus same-class fallbacks.
Calculators
Drugs
Pathways
- New-Onset Atrial Fibrillation · ESC 2020 AF Guidelines; NICE NG196
- Hypertensive Emergency · ESC/ESH 2018 Hypertension Guidelines; NICE NG136
- Bradycardia Management · Resuscitation Council UK ABCDE; ESC 2021 Pacing Guidelines
- Ventricular Tachycardia / Fibrillation · Resuscitation Council UK ACLS; ESC 2022 Ventricular Arrhythmia Guidelines
- Syncope Assessment · ESC 2018 Syncope Guidelines; NICE NG109
- Acute Chest Pain · NICE CG95; ESC 2023 ACS Guidelines