Non-sedating H1 antihistamine
Mizolastine
Brand names: Mizollen
Adult dose
Dose: 10mg PO OD
Route: PO
Frequency: OD
Clinical pearls
- Allergic rhinitis, urticaria — alternative to fexofenadine/loratadine
Contraindications
- Significant hepatic impairment
- Concurrent QT-prolonging drugs / strong CYP3A4 inhibitors
- Hypokalaemia
- Symptomatic arrhythmia
- Bradycardia
Side effects
- QT prolongation
- Headache
- Drowsiness
- Weight gain
Interactions
- QT-prolonging drugs
- Strong CYP3A4 inhibitors
Reference: BNF; https://bnf.nice.org.uk/drugs/mizolastine/. Verify against your local formulary and the latest BNF before prescribing.
Related
Curated clinical cross-links plus same-class fallbacks.
Calculators
Drugs
Pathways
- New-Onset Atrial Fibrillation · ESC 2020 AF Guidelines; NICE NG196
- Hypertensive Emergency · ESC/ESH 2018 Hypertension Guidelines; NICE NG136
- Bradycardia Management · Resuscitation Council UK ABCDE; ESC 2021 Pacing Guidelines
- Ventricular Tachycardia / Fibrillation · Resuscitation Council UK ACLS; ESC 2022 Ventricular Arrhythmia Guidelines
- Syncope Assessment · ESC 2018 Syncope Guidelines; NICE NG109
- Acute Chest Pain · NICE CG95; ESC 2023 ACS Guidelines