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IV fluid (mixed)

Potassium chloride with glucose and sodium chloride

Adult dose

Dose: Per maintenance regime — e.g. 1L 4% dextrose / 0.18% NaCl + 20 mmol KCl over 8–12h (paediatric)
Route: IV
Frequency: per indication

Clinical pearls

  • Largely withdrawn from paediatric use — 0.9% NaCl + glucose preferred
  • Adult maintenance only with electrolyte monitoring

Contraindications

  • Hyperkalaemia
  • Hyponatraemia (severe)
  • DKA (initial)

Side effects

  • Hyponatraemia (esp. in children — never use 0.18% NaCl in paeds since 2007 alert)
  • Hyperkalaemia
  • Hyperglycaemia

Interactions

  • ACEi/ARB
  • Insulin

Monitoring

  • Na+
  • K+
  • Glucose

Reference: BNF; NICE CG174/NG29; NPSA alert 2007; https://bnf.nice.org.uk/drugs/potassium-chloride-with-glucose-and-sodium-chloride/. Verify against your local formulary and the latest BNF before prescribing.

Related

Curated clinical cross-links plus same-class fallbacks.