Ferrous Sulphate
Brand names: Ferrograd (200mg), Ironorm Drops, Sytron (ferrous fumarate liquid)
Ferrous sulphate is an oral iron salt used to treat iron-deficiency anaemia.
ClinCalc Pro is rebuilding its dose data from primary open sources — the manufacturer SmPC (eMC), the WHO Model Formulary and other official references — under clinician review. This drug's structured dose is not yet published here. Confirm all doses against the product SmPC and your local formulary before prescribing.
US labelling (FDA)
Reference — US labelling, may differ from UKAdults and children: At the onset of symptoms, dissolve 5 pellets under the tongue 3 times a day until symptoms are relieved or as directed by a doctor.
Source: US FDA prescribing information (openFDA / DailyMed), label dated 2025-07-21. Accessed 2026-06-12. US dosing and indications can differ from UK practice — use UK sources for prescribing decisions.
Clinical monograph
How it works
It provides elemental iron for haemoglobin synthesis, correcting iron-deficiency anaemia.
Prescribing in practice
- Gastrointestinal effects (nausea, constipation, dark stools) are common and dose-related; a lower dose or alternate-day dosing can improve tolerance and may improve absorption.
- Absorption is reduced by tea, calcium, antacids and some other drugs — separate their timing.
- Continue treatment for a period after the haemoglobin normalises to replenish iron stores, and investigate the underlying cause.
Monitoring
Monitor haemoglobin and iron stores (ferritin) to confirm response; investigate the cause of the deficiency.
Counselling the patient
- Stools may turn black, which is harmless.
- Taking it with a source of vitamin C (e.g. orange juice) aids absorption; avoid taking it with tea or coffee.
- Keep iron away from children — overdose is dangerous.
Evidence & guidelines
Oral iron is first-line for iron-deficiency anaemia; lower-dose or alternate-day regimens are increasingly preferred for tolerability and absorption.
Reference: NICE NG24 (Anaemia in CKD); BSH Guidelines on Iron Deficiency Anaemia; Drug verified in RxNorm (NLM); confirm dosing against the manufacturer SPC (eMC). Verify against your local formulary and current prescribing references before prescribing. Monograph status: clinician-reviewed (2026-07-04).
Related
Curated clinical cross-links plus same-class fallbacks.
- DOAC Score for Selecting Direct Oral Anticoagulant in Non-Valvular AF · Anticoagulation
- Corrected Reticulocyte Count / Reticulocyte Production Index · Anaemia
- Ganzoni Equation for Iron Deficiency · Anaemia
- Transferrin Saturation Calculator · Anaemia / Iron Studies
- Iron Deficiency Anaemia Calculator · Anaemia Assessment
- Ferritin Iron Store Interpretation · Haematological Values
- Sepsis Screening and Sepsis Six · UK Sepsis Trust; NICE NG51; Surviving Sepsis Campaign 2021
- Unintentional Weight Loss Workup · NICE NG12; BSG
- Chronic Fatigue Workup · NICE NG206; BMJ Best Practice
- Lymphadenopathy Workup · NICE NG12; BMJ Best Practice
- Pre-op Medical Clearance · NICE NG45; ESC 2022
- Secondary Hypertension Workup · NICE NG136; ESH 2023