Low molecular weight heparin (LMWH)
Bemiparin sodium
Brand names: Zibor
Adult dose
Dose: VTE prophylaxis: 2,500–3,500 units SC OD; Treatment: 115 units/kg SC OD
Route: Subcutaneous
Frequency: OD
Clinical pearls
- NICE NG89 / NG158 — alternative LMWH
- BSH guidance
- Less commonly used in UK than enoxaparin/dalteparin/tinzaparin
Contraindications
- Active major bleeding
- HIT history
- CrCl <30
- Severe hepatic impairment
- Hypersensitivity
Side effects
- Bleeding
- HIT
- Hyperkalaemia
- Injection-site reactions
- Osteoporosis (long-term)
Interactions
- Anticoagulants/antiplatelets/NSAIDs
- ACEi/ARB
Monitoring
- FBC (HIT)
- Renal function
- Bleeding
Reference: BNF; NICE NG89; NG158; BSH; https://bnf.nice.org.uk/drugs/bemiparin-sodium/. Verify against your local formulary and the latest BNF before prescribing.
Related
Curated clinical cross-links plus same-class fallbacks.
Calculators
- Endotracheal Tube Depth and Tidal Volume Calculator · Airway Management
- IMPROVE VTE Risk Score for Medical Patients · VTE Risk
- Corrected Sodium (Hyperglycaemia) · Electrolytes
- BMI + Metabolic Risk Assessment · Obesity
- Ideal & Adjusted Body Weight · Body Composition
- Weight-Based Levothyroxine Dose Calculator · Thyroid
Drugs
Pathways
- Major Haemorrhage / Massive Transfusion · BCSH; RCOA; RCEM; RCS — BCSH Guidelines
- Anaemia Investigation · BSH / NICE
- Splenomegaly Workup · BSH; BMJ Best Practice
- Deep Vein Thrombosis Diagnosis and Treatment · NICE CG144 / NICE NG158
- Sickle Cell Crisis · BSH 2021 / BCSH
- Neutropenic Sepsis · NICE CG151 2012 / ESMO