IV iron
Ferric derisomaltose
Brand names: Monofer
Adult dose
Dose: Up to 20 mg/kg as single infusion (over ≥20 min), or 1000mg as infusion
Route: IV
Frequency: per replacement
Clinical pearls
- Lower hypophosphataemia risk than ferric carboxymaltose
- Single high-dose total replacement possible
Contraindications
- 1st trimester pregnancy
- Iron overload
- Severe hypersensitivity to IV iron
Side effects
- Hypersensitivity
- Hypophosphataemia (less common than ferric carboxymaltose)
- Headache
- Nausea
Interactions
- Oral iron — separate by ≥5 days
Monitoring
- Ferritin
- TSAT
- Hb
Reference: BNF; NICE NG8; https://bnf.nice.org.uk/drugs/ferric-derisomaltose/. Verify against your local formulary and the latest BNF before prescribing.
Related
Curated clinical cross-links plus same-class fallbacks.
Calculators
Pathways
- Major Haemorrhage / Massive Transfusion · BCSH; RCOA; RCEM; RCS — BCSH Guidelines
- Anaemia Investigation · BSH / NICE
- Splenomegaly Workup · BSH; BMJ Best Practice
- Deep Vein Thrombosis Diagnosis and Treatment · NICE CG144 / NICE NG158
- Sickle Cell Crisis · BSH 2021 / BCSH
- Neutropenic Sepsis · NICE CG151 2012 / ESMO