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PG analogue + beta-blocker eye drops

Bimatoprost with timolol

Brand names: Ganfort

Adult dose

Dose: 1 drop OD
Route: Ophthalmic
Frequency: OD

Clinical pearls

  • NICE NG81 glaucoma: combination drops to reduce drop burden
  • RCOphth

Contraindications

  • Severe asthma
  • Bradyarrhythmia / heart block
  • Heart failure
  • Hypersensitivity

Side effects

  • Conjunctival hyperaemia
  • Iris darkening
  • Bronchospasm (timolol)
  • Bradycardia
  • Fatigue
  • Depression

Interactions

  • Systemic beta-blockers
  • Verapamil/diltiazem
  • Insulin/oral hypoglycaemics

Monitoring

  • IOP
  • Visual fields
  • HR / BP
  • Asthma symptoms

Reference: BNF; NICE NG81; RCOphth; https://bnf.nice.org.uk/drugs/bimatoprost-with-timolol/. Verify against your local formulary and the latest BNF before prescribing.

Related

Curated clinical cross-links plus same-class fallbacks.