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Haematology Strong — IMWG R-ISS 2015

Revised ISS (R-ISS) for Multiple Myeloma

Revised International Staging System for Multiple Myeloma incorporating ISS stage, LDH, and high-risk cytogenetics.

ISS I: β2M < 3.5 mg/L + albumin ≥ 35 g/L; ISS III: β2M ≥ 5.5 mg/L; ISS II: all others

High-risk: del(17p), t(4;14), t(14;16) on FISH

References

Related

Curated clinical cross-links plus same-class fallbacks.

Decision support only — verify against MDCalc, NICE, or your local guideline before clinical use.