Surgery Drugs

70 drugs

Quick-reference dosing for 70 surgery medicines, aligned to current UK formularies. Each entry lists adult, paediatric and (where relevant) neonatal doses, renal and hepatic adjustments, contraindications, key interactions, monitoring and clinical pearls — with the source reference. Always confirm doses against current prescribing references before prescribing.

Aprepitant

NK1 Receptor Antagonist (Antiemetic)
Aprotinin

Antifibrinolytic — Cardiac Surgery
Atracurium

Non-Depolarising Neuromuscular Blocking Agent
Bisacodyl

Stimulant Laxative — Bowel Preparation / Post-operative
Bupivacaine

Long-Acting Local Anaesthetic (Amide)
Buprenorphine (Surgical — Analgesia)

Opioid Analgesic (Partial Agonist)
Cefazolin (Surgical Prophylaxis)

1st Generation Cephalosporin (Surgical Antibiotic Prophylaxis)
Cefepime (Surgical — Broad-Spectrum Cover)

Fourth-Generation Cephalosporin
Cefuroxime

Antibiotic (2nd Generation Cephalosporin)
Celecoxib

COX-2 Selective NSAID — Perioperative Analgesia
Clindamycin (Surgical Prophylaxis — Penicillin Allergy)

Antibiotic (Lincosamide) — Surgical Prophylaxis
Clonidine

Alpha-2 Agonist — Analgesic Adjunct / Sedation
Co-codamol 30/500 (Post-Operative Step-Down Analgesia)

Compound Analgesic (Codeine + Paracetamol — Weak Opioid Step-Down)
Dalteparin (Perioperative VTE Prophylaxis)

Low Molecular Weight Heparin — VTE Prophylaxis
Desmopressin (Surgical — Haemostasis/Platelet Dysfunction)

Vasopressin Analogue V2 (Antidiuretic/Haemostatic)
Dexamethasone (PONV Prevention)

Corticosteroid (Antiemetic)
Dexmedetomidine

Alpha-2 Agonist Sedative / Analgesic
Diclofenac (Perioperative)

NSAID — Perioperative Analgesia
Droperidol

Butyrophenone Antiemetic — PONV
Enoxaparin (VTE Prophylaxis — Post-Surgery)

Low Molecular Weight Heparin (LMWH) — VTE Prophylaxis
Fentanyl (Perioperative Analgesia)

Opioid Analgesic (Short-Acting — Perioperative)
Fibrinogen Concentrate (Riastap)

Coagulation Factor — Haemostatic Agent
Fondaparinux (Surgical VTE Prophylaxis)

Anticoagulant — Factor Xa Inhibitor (Indirect)
Gabapentin (Perioperative)

Anticonvulsant / Perioperative Analgesic Adjunct
Gentamicin

Antibiotic (Aminoglycoside)
Glycopyrronium (Perioperative — Anticholinergic)

Anticholinergic (Muscarinic Antagonist) — Perioperative
Heparin Unfractionated (Prophylaxis)

Anticoagulant — VTE Prophylaxis (UFH)
Human Albumin Solution (Surgical — Volume/Oncotic)

Plasma Protein Solution — Colloid
Hydrocortisone with lidocaine

Topical steroid + local anaesthetic
Hydrogen peroxide

Topical antiseptic / oxidising agent
Ibuprofen (Multimodal Post-Operative Analgesia)

Non-Selective NSAID (Non-Opioid Analgesic)
Ketamine (Perioperative — Opioid-Sparing Analgesia)

NMDA Receptor Antagonist (Dissociative Anaesthetic / Analgesic)
Ketorolac Trometamol

NSAID — Parenteral Analgesic
Lauromacrogol 400 (polidocanol)

Sclerosant
Levobupivacaine

Long-Acting Local Anaesthetic (Amide)
Lidocaine (IV Infusion — Opioid-Sparing Analgesia)

Local Anaesthetic (IV Systemic — Opioid-Sparing / Anti-inflammatory)
Macrogol (Polyethylene Glycol)

Osmotic Laxative — Bowel Preparation / Constipation
Mannitol (Surgical — ICP/Osmotherapy)

Osmotic Diuretic
Meropenem

Antibiotic (Carbapenem)
Methylprednisolone (Surgical — Anti-Inflammatory)

Corticosteroid (Systemic — IV)
Metoclopramide (Perioperative PONV)

Dopamine D2 Antagonist / Prokinetic (Antiemetic)
Metronidazole

Antibiotic (Nitroimidazole)
Midazolam (Surgical — Anxiolysis/Sedation)

Benzodiazepine — Short-Acting Sedative
Morphine (PCA — Post-Operative Pain)

Opioid Analgesic — Patient-Controlled Analgesia
Neostigmine

Acetylcholinesterase Inhibitor / Neuromuscular Blockade Reversal
Neostigmine (with Glycopyrronium)

Anticholinesterase — Neuromuscular Blockade Reversal
Norepinephrine (Noradrenaline — Perioperative Vasopressor)

Vasopressor (Alpha-1 Adrenoceptor Agonist)
Octreotide (Surgical — Fistula/Carcinoid)

Somatostatin Analogue
Omeprazole (Perioperative — Aspiration Prophylaxis)

Proton Pump Inhibitor — Aspiration Prophylaxis
Ondansetron (Perioperative)

5-HT3 Receptor Antagonist (Antiemetic)
Oxycodone

Opioid Analgesic (Moderate-Strong)
Paracetamol (IV)

Non-Opioid Analgesic / Antipyretic — IV
Parecoxib

COX-2 Selective NSAID (Parenteral)
Phytomenadione (Vitamin K1)

Vitamin K — Anticoagulant Reversal / Haemostasis
Piperacillin-Tazobactam

Antibiotic (Extended-Spectrum Penicillin + Beta-Lactamase Inhibitor)
Pregabalin (Perioperative)

Anticonvulsant / Perioperative Analgesic Adjunct
Propofol

IV Induction and Maintenance Agent
Ranitidine / Famotidine (H2 Antagonist — Aspiration Prophylaxis)

H2 Receptor Antagonist — Aspiration Prophylaxis
Remifentanil

Ultra-Short Acting Opioid Analgesic
Rivaroxaban (Perioperative VTE Prophylaxis)

Direct Oral Anticoagulant — VTE Prophylaxis Post-Surgery
Ropivacaine

Long-Acting Local Anaesthetic (Amide)
Sodium Picosulfate

Stimulant Laxative — Bowel Preparation
Sugammadex

Neuromuscular Blockade Reversal
Teicoplanin (Surgical Prophylaxis/MRSA)

Glycopeptide Antibiotic
Thiopental Sodium

IV Induction Agent (Barbiturate)
Tramadol (Post-Operative Pain)

Weak Opioid / Serotonin-Noradrenaline Reuptake Inhibitor (Analgesic)
Tranexamic Acid (Surgical / Trauma Haemorrhage)

Antifibrinolytic (Haemostatic)
Vancomycin

Antibiotic (Glycopeptide)
Vasopressin (Surgical — Vasopressor/Haemostasis)

Vasopressin Receptor Agonist (V1/V2)
Vecuronium

Non-Depolarising Neuromuscular Blocking Agent