Antimuscarinic (overactive bladder)
Fesoterodine fumarate
Brand names: Toviaz
Adult dose
Dose: 4mg OD initially, increase to 8mg if needed
Route: PO
Frequency: OD
Dose adjustments
Renal
Severe renal impairment: max 4mg OD
Clinical pearls
- Alternative to oxybutynin/solifenacin
- Mirabegron preferred in older adults to reduce anticholinergic burden
Contraindications
- Urinary retention
- Gastric retention
- Uncontrolled angle-closure glaucoma
- Myasthenia gravis
- Severe hepatic impairment
Side effects
- Dry mouth
- Constipation
- Dyspepsia
- Urinary retention
Interactions
- Strong CYP3A4 inhibitors (max 4mg)
- Other antimuscarinics — additive load
Reference: BNF; NICE NG123; https://bnf.nice.org.uk/drugs/fesoterodine-fumarate/. Verify against your local formulary and the latest BNF before prescribing.
Related
Curated clinical cross-links plus same-class fallbacks.
Calculators
Drugs