Skip to content
ClinCalc Pro
Menu
RheumatologyRenal

Scleroderma Renal Crisis

Acute hypertension + AKI in systemic sclerosis — urgent ACE-I (lifesaving), avoid steroids >15 mg/day.

Source: EULAR 2023; UK Scleroderma Study Group

Used in: Hypertension Acute Kidney Injury
Step 1 of ~2
info

Recognise

Risk: diffuse cutaneous SSc <4 years from onset, anti-RNA polymerase III antibody, recent corticosteroid (especially >15 mg/day prednisolone). Sudden severe hypertension (often >200/120) + AKI + microangiopathic haemolytic anaemia + thrombocytopenia + headache + visual change + LV dysfunction. Always check BP at every clinical visit in SSc — early detection saves lives.

Related

Curated clinical cross-links plus same-class fallbacks.

Decision support only. Always apply local guidelines and clinical judgement.