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Haematology A

FLIPI — Follicular Lymphoma International Prognostic Index

Predicts overall survival in follicular lymphoma. Based on 5 adverse factors.

Score interpretation

Low Risk 0–1

Low risk. 10-year OS ~71%.

→ Watch and wait or rituximab monotherapy. Consider clinical trial enrolment.

Intermediate Risk 2

Intermediate risk. 10-year OS ~51%.

→ Chemoimmunotherapy (R-CHOP, R-bendamustine) as per ESMO/NICE guidelines. Maintenance rituximab.

High Risk 3–5

High risk. 10-year OS ~36%.

→ Intensive chemoimmunotherapy. Consider clinical trial. Haematology specialist centre referral.

Interpretation bands for the FLIPI. Apply clinical judgement and local guidance.

References

Related

Curated clinical cross-links plus same-class fallbacks.

Decision support only — verify against a current formulary, NICE, or your local guideline before clinical use.